Literature DB >> 3926332

The effects of arotinoids on rat mammary carcinogenesis.

H R Hartmann, W Bollag.   

Abstract

The influence of two retinoids, Ro 13-6298, an arotinoid ethyl ester, and Ro 15-1570, an arotinoid ethyl sulfone, on rat mammary carcinogenesis was investigated. Mammary carcinomas were induced by oral administration of 15 mg dimethylbenz(a)anthracene (DMBA) to 50-day-old female Sprague-Dawley rats. Oral administration of the two retinoids significantly inhibited the development of tumors. The number and volume of mammary neoplasms were influenced in a dose-dependent manner.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3926332     DOI： 10.1007/bf00257524

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  9 in total

1.  Role of retinoids in differentiation and carcinogenesis.

Authors:  M B Sporn; A B Roberts
Journal:  Cancer Res       Date:  1983-07       Impact factor: 12.701

2.  Structure-activity relationships of a new series of retinoidal benzoic acid derivatives as measured by induction of differentiation of murine F9 teratocarcinoma cells and human HL-60 promyelocytic leukemia cells.

Authors:  S Strickland; T R Breitman; F Frickel; A Nürrenbach; E Hädicke; M B Sporn
Journal:  Cancer Res       Date:  1983-11       Impact factor: 12.701

3.  Inhibition of 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis by retinyl acetate.

Authors:  R C Moon; C J Grubbs; M B Sporn
Journal:  Cancer Res       Date:  1976-07       Impact factor: 12.701

4.  Inhibition of mammary cancer by retinyl methyl ether.

Authors:  C J Grubbs; R C Moon; M B Sporn; D L Newton
Journal:  Cancer Res       Date:  1977-02       Impact factor: 12.701

5.  Distribution of retinoic acid-binding proteins in normal and neoplastic mammary tissues.

Authors:  R G Mehta; W L Cerny; R C Moon
Journal:  Cancer Res       Date:  1980-01       Impact factor: 12.701

6.  N-(4-Hydroxyphenyl)retinamide, a new retinoid for prevention of breast cancer in the rat.

Authors:  R C Moon; H J Thompson; P J Becci; C J Grubbs; R J Gander; D L Newton; J M Smith; S L Phillips; W R Henderson; L T Mullen; C C Brown; M B Sporn
Journal:  Cancer Res       Date:  1979-04       Impact factor: 12.701

7.  Arotinoids. A new class of retinoids with activities in oncology and dermatology.

Authors:  W Bollag
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

8.  Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.

Authors:  D L McCormick; R G Mehta; C A Thompson; N Dinger; J A Caldwell; R C Moon
Journal:  Cancer Res       Date:  1982-02       Impact factor: 12.701

9.  Synergistic effect of chronic prolactin suppression and retinoid treatment in the prophylaxis of N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.

Authors:  C W Welsch; C K Brown; M Goodrich-Smith; J Chiusano; R C Moon
Journal:  Cancer Res       Date:  1980-09       Impact factor: 12.701
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.