| Literature DB >> 3924878 |
S R Rohlfing, J E Landmesser, J F Gerster, S E Pecore, R M Stern.
Abstract
Clinical isolates of Neisseria gonorrhoeae were tested for growth inhibition by various quinolones. One acrosoxacin-resistant isolate was also resistant to several fluorinated quinolones with 7-heterocyclic substitution, but, inhibitory concentrations were not elevated for quinolones substituted with a methyl group in the corresponding position (nalidixic acid:position 7, S-25930:position 8) or unsubstituted (flumequine:position 8). Isolates resistant to flumequine demonstrated elevated inhibitory concentrations for all quinolones examined.Entities:
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Year: 1985 PMID： 3924878 DOI： 10.1093/jac/15.5.539
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790