Literature DB >> 392480

Evaluation of vaginal antifungal formulations in vivo.

R J McRipley, P J Erhard, R A Schwind, R R Whitney.   

Abstract

Relatively simple and rapid procedures have been developed for evaluating the local efficacy of vaginal antifungal agents in vivo in a vaginal candidiasis model in ovariectomized rats. The results of this investigation indicate that the model and methods described are quite suitable for screening potential antifungal substances and for assessing the chemotherapeutic effectiveness of new antifungal agents and formulations before carrying out clinical studies.

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Year:  1979        PMID: 392480      PMCID: PMC2425650          DOI: 10.1136/pgmj.55.647.648

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  3 in total

1.  [Chemotherapy of vaginal trichomoniasis and candidiasis in mice].

Authors:  A Wildfeuer
Journal:  Arzneimittelforschung       Date:  1974-06

2.  Experimental vaginal candidiasis in mice; its implications for superficial candidiasis in humans.

Authors:  C L TASCHDJIAN; F REISS; P J KOZINN
Journal:  J Invest Dermatol       Date:  1960-02       Impact factor: 8.551

3.  Synergism of polyene antibiotics with 5-fluorocytosine.

Authors:  A Polak
Journal:  Chemotherapy       Date:  1978       Impact factor: 2.544

  3 in total
  3 in total

1.  Effects of reproductive hormones on experimental vaginal candidiasis.

Authors:  P L Fidel; J Cutright; C Steele
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

2.  Hormonal factors in vaginal candidiasis in rats.

Authors:  O S Kinsman; A E Collard
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

3.  Comparison of ketoconazole, Bay N7133, and Bay L9139 in the treatment of experimental vaginal candidiasis.

Authors:  J D Sobel; G Muller
Journal:  Antimicrob Agents Chemother       Date:  1983-09       Impact factor: 5.191

  3 in total

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