Literature DB >> 3924649

Microbial methylation of benzenethiols and release of methylthiobenzenes.

A M Drotar, R Fall.   

Abstract

Three phylogenetically diverse microorganisms methylated several different chloro- and nitro-substituted benzenethiols to yield the corresponding methylthiobenzenes. These products were identified by gas chromatography-mass spectrometry. In several cases large percentages of the methylthio products were released by intact cells into the medium, suggesting that microbial methylation of xenobiotic thiols may be a significant biotransformation in many ecosystems.

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Year:  1985        PMID: 3924649     DOI: 10.1007/bf02012585

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

1.  Thiol S-methyltransferase: suggested role in detoxication of intestinal hydrogen sulfide.

Authors:  R A Weisiger; L M Pinkus; W B Jakoby
Journal:  Biochem Pharmacol       Date:  1980-10-15       Impact factor: 5.858

2.  Biodegradation of chemicals of environmental concern.

Authors:  M Alexander
Journal:  Science       Date:  1981-01-09       Impact factor: 47.728

3.  Cysteine conjugate beta-lyase in rat liver. A novel enzyme catalyzing formation of thiol-containing metabolites of drugs.

Authors:  M Tateishi; S Suzuki; H Shimizu
Journal:  J Biol Chem       Date:  1978-12-25       Impact factor: 5.157

4.  Studies on the toxicology of hexachlorobenzene. IV. Sulphur-containing metabolites.

Authors:  G Koss; W Koransky; K Steinbach
Journal:  Arch Toxicol       Date:  1979-04-23       Impact factor: 5.153

5.  Methylthio metabolites of naphthalen excreted by the rat.

Authors:  W G Stillwell; O J Bouwsma; J P Thenot; M G Horning; G W Griffin; K Ishikawa; M Takaku
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1978-06

6.  Metabolism of 2,2',5,5'-tetrachlorobiphenyl: formation of mono- and bis-methyl sulphone metabolites with a selective affinity for the lung and kidney tissues in mice.

Authors:  A Bergman; I Brandt; P O Darnerud; C A Wachtmeister
Journal:  Xenobiotica       Date:  1982-01       Impact factor: 1.908

7.  Metabolism of 2-chloro-N-isopropylacetanilide (propachlor) in the rat.

Authors:  J E Bakke; C E Price
Journal:  J Environ Sci Health B       Date:  1979       Impact factor: 1.990

Review 8.  Biotransformation of the fungicides hexachlorobenzene and pentachloronitrobenzene.

Authors:  G Renner
Journal:  Xenobiotica       Date:  1981-07       Impact factor: 1.908

  8 in total
  2 in total

1.  Methylation of halogenated phenols and thiophenols by cell extracts of gram-positive and gram-negative bacteria.

Authors:  A H Neilson; C Lindgren; P A Hynning; M Remberger
Journal:  Appl Environ Microbiol       Date:  1988-02       Impact factor: 4.792

2.  Enzymatic methylation of sulfide, selenide, and organic thiols by Tetrahymena thermophila.

Authors:  A Drotar; L R Fall; E A Mishalanie; J E Tavernier; R Fall
Journal:  Appl Environ Microbiol       Date:  1987-09       Impact factor: 4.792

  2 in total

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