Literature DB >> 3924468

Gold: hepatotoxic and cholestatic reactions.

A S Hanissian, B M Rothschild, S Kaplan.   

Abstract

Gold hepatotoxicity is an uncommon but significant clinical problem. Hepatitis was first manifested one day to four weeks after the last dose of gold at a cumulative range of 35 to 2900 mg. An interesting dichotomy was noted between cholestatic and hepatotoxic reactions. Hepatotoxic reactions were associated with other clinical signs of hypersensitivity, thus facilitating differential diagnosis from viral hepatitis. Sudden clinical improvement in a patient receiving gold should stimulate evaluation for a hepatotoxic reaction.

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Year:  1985        PMID： 3924468     DOI： 10.1007/bf02032291

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  16 in total

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Journal:  Helv Med Acta       Date:  1960-12

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Journal:  Am J Pathol       Date:  1961-04       Impact factor: 4.307

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Authors:  K M Goel; R A Shanks
Journal:  Ann Rheum Dis       Date:  1974-01       Impact factor: 19.103

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Authors:  J Ghisolfi; J L Rumeau; M Rolland; A Dalous
Journal:  Arch Fr Pediatr       Date:  1972-12

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Authors:  D L Howrie; J C Gartner
Journal:  J Rheumatol       Date:  1982 Sep-Oct       Impact factor: 4.666

7.  Treatment of juvenile rheumatoid arthritis -- a world survey.

Authors:  J J Orozco-Alcala; J Baum
Journal:  J Rheumatol       Date:  1974-06       Impact factor: 4.666

8.  [Anatomo-pathologic aspects of gold-salt induced cholestasis. Report of two cases with ultrastructural study (author's transl)].

Authors:  M F Le Bodic; C Degott; J Barrier; G Chekroun; F Gaillard; F Couprie; J Mussini-Montpellier
Journal:  Arch Anat Cytol Pathol       Date:  1981

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Authors:  S Charhon; M Rouillat; M Bouvier
Journal:  Rev Rhum Mal Osteoartic       Date:  1980-03

10.  A forensic pathology slide seminar.

Authors:  J E Campbell
Journal:  J Forensic Sci       Date:  1966-10       Impact factor: 1.832
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