Literature DB >> 3922076

Purification of a specific placental plasminogen activator inhibitor by monoclonal antibody and its complex formation with plasminogen activator.

B Astedt, I Lecander, T Brodin, A Lundblad, K Löw.   

Abstract

A monoclonal antibody of IgG2a-type was obtained against a specific fast acting plasminogen activator inhibitor found in placenta. The placental inhibitor was purified by affinity chromatography using the monoclonal antibody and additionally in a FPLC-system. A strong complex formation was found between the inhibitor and urokinase and also with the two-chain form of plasminogen activator of the tissue-type. A weaker complex was found between the placental inhibitor and the one-chain form of the tissue-type activator.

Mesh：

Substances：

Year:  1985        PMID： 3922076

Source DB:  PubMed          Journal:  Thromb Haemost        ISSN： 0340-6245            Impact factor:   5.249


  22 in total

1.  Cloning and sequence of a cDNA coding for the human beta-migrating endothelial-cell-type plasminogen activator inhibitor.

Authors:  T Ny; M Sawdey; D Lawrence; J L Millan; D J Loskutoff
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

2.  cDNA cloning of human plasminogen activator-inhibitor from endothelial cells.

Authors:  D Ginsburg; R Zeheb; A Y Yang; U M Rafferty; P A Andreasen; L Nielsen; K Dano; R V Lebo; T D Gelehrter
Journal:  J Clin Invest       Date:  1986-12       Impact factor: 14.808

3.  Plasminogen activator inhibitor is associated with the extracellular matrix of cultured bovine smooth muscle cells.

Authors:  B S Knudsen; P C Harpel; R L Nachman
Journal:  J Clin Invest       Date:  1987-10       Impact factor: 14.808

4.  Plasminogen activator inhibitor type 1 biosynthesis and mRNA level are increased by dexamethasone in human fibrosarcoma cells.

Authors:  P A Andreasen; C Pyke; A Riccio; P Kristensen; L S Nielsen; L R Lund; F Blasi; K Danø
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

5.  Opposite and independent actions of cyclic AMP and transforming growth factor beta in the regulation of type 1 plasminogen activator inhibitor expression.

Authors:  F W Thalacker; M Nilsen-Hamilton
Journal:  Biochem J       Date:  1992-11-01       Impact factor: 3.857

6.  Kinetic analysis of the interaction between plasminogen activator inhibitor-1 and tissue-type plasminogen activator.

Authors:  C Masson; E Angles-Cano
Journal:  Biochem J       Date:  1988-11-15       Impact factor: 3.857

7.  Cloning and expression of a cDNA coding for a human monocyte-derived plasminogen activator inhibitor.

Authors:  T M Antalis; M A Clark; T Barnes; P R Lehrbach; P L Devine; G Schevzov; N H Goss; R W Stephens; P Tolstoshev
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

Review 8.  Clinical disorders of fibrinolysis: a critical review.

Authors:  R B Francis
Journal:  Blut       Date:  1989-07

9.  Influence of various structural domains of fibrinogen and fibrin on the potentiation of plasminogen activation by recombinant tissue plasminogen activator.

Authors:  V S de Serrano; T Urano; P J Gaffney; F J Castellino
Journal:  J Protein Chem       Date:  1989-02

Review 10.  Activities, localizations, and roles of serine proteases and their inhibitors in human brain tumor progression.

Authors:  M Yamamoto; R Sawaya; S Mohanam; V H Rao; J M Bruner; G L Nicolson; K Ohshima; J S Rao
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.