Literature DB >> 3922063

Sodium valproate poisoning. A case report.

A C van der Merwe, C F Albrecht, M S Brink, A R Coetzee.   

Abstract

A case of a severe overdose of sodium valproate (more than 10 times the therapeutic requirement) is discussed. The patient presented with central nervous, respiratory and cardiovascular depression and was treated with supportive therapy and haemoperfusion. However, on available data it would appear that haemoperfusion did not make a significant contribution towards the patient's recovery.

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Year:  1985        PMID: 3922063

Source DB:  PubMed          Journal:  S Afr Med J


  3 in total

1.  Case files of the Children's Hospital of Michigan Regional Poison Control Center: the use of carnitine for the management of acute valproic acid toxicity.

Authors:  Abhishek Katiyar; Cynthia Aaron
Journal:  J Med Toxicol       Date:  2007-09

2.  Acute valproic acid overdose. Clinical course and pharmacokinetic disposition of valproic acid and metabolites.

Authors:  R E Dupuis; S N Lichtman; G M Pollack
Journal:  Drug Saf       Date:  1990 Jan-Feb       Impact factor: 5.606

3.  A case of valproate intoxication with excessive brain edema.

Authors:  G Hintze; H H Klein; H Prange; H Kreuzer
Journal:  Klin Wochenschr       Date:  1987-05-04
  3 in total

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