Literature DB >> 3921456

Recombinant human interleukin 2 acts as a B cell growth and differentiation promoting factor.

F Emmrich, H Moll, M M Simon.   

Abstract

Human B cells appropriately activated by a B cell mitogen are rendered susceptible to human Interleukin 2 (IL-2) as demonstrated with recombinant human IL-2 (rec. h IL-2). They show increased proliferation and drastically enhanced immunoglobulin secretion. Susceptibility to IL-2 is accompanied with the expression of the IL-2 receptor (Tac antigen) on B cells. The data suggest that IL-2 is one of the lymphokines directly involved in the activation of B lymphocytes.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3921456     DOI： 10.1016/S0171-2985(85)80057-7

Source DB:  PubMed          Journal:  Immunobiology        ISSN： 0171-2985            Impact factor:   3.144


  8 in total

Review 1.  Surface antigens associated with human B cell activation.

Authors:  L K Jung
Journal:  Immunol Res       Date:  1986       Impact factor: 2.829

2.  The effect of anti-CD4 on helper function of CD4,45RA+ versus CD4,45RO+ T cells.

Authors:  J Wang; T Yan; B Simmer; F Emmrich
Journal:  Clin Exp Immunol       Date:  1994-01       Impact factor: 4.330

3.  Proliferation and immunoglobulin synthesis of peripheral blood mononuclear cells from patients with chronic liver disease stimulated by Staphylococcus aureus Cowan 1 and interleukin 2.

Authors:  S Kakumu; A Fuji; Y Ohtani; K Murase; H Hirofuji; H Tahara
Journal:  Gastroenterol Jpn       Date:  1987-06

4.  Immunomodulatory effects of systemic low-dose recombinant interleukin-2 and lymphokine-activated killer cells in humans.

Authors:  T J Eberlein; M L Rodrick; A F Massaro; S E Jung; J A Mannick; D D Schoof
Journal:  Cancer Immunol Immunother       Date:  1989       Impact factor: 6.968

5.  Improved in vivo efficacy of tumor-infiltrating lymphocytes after restimulation with irradiated tumor cells in vitro.

Authors:  U L Burger; M P Chang; M Nagoshi; P S Goedegebuure; T J Eberlein
Journal:  Ann Surg Oncol       Date:  1996-11       Impact factor: 5.344

6.  Expression of CD117 (c-Kit) on Circulating B Cells in Pediatric Schistosomiasis.

Authors:  Isaac O Onkanga; Rachael Hamilton; Pauline N M Mwinzi; Thomas Schneider; Bartholomew N Ondigo; Huldah Sang; Edna Ondari; Fredrick Rawago; Walter Jaoko; Maurice R Odiere; Lisa Ganley-Leal
Journal:  Infect Immun       Date:  2022-07-06       Impact factor: 3.609

7.  Modulation of cellular immune responses in mice with disseminated histoplasmosis by recombinant interleukin-2.

Authors:  G S Deepe; C L Taylor; J E Harris; W E Bullock
Journal:  Infect Immun       Date:  1986-07       Impact factor: 3.441

8.  Enriching leukapheresis improves T cell activation and transduction efficiency during CAR T processing.

Authors:  Elsa Noaks; Carlotta Peticone; Ekaterini Kotsopoulou; Daniel G Bracewell
Journal:  Mol Ther Methods Clin Dev       Date:  2021-02-06       Impact factor: 6.698
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.