Literature DB >> 3919496

Enhanced intraphagocytic killing of Brucella abortus in bovine mononuclear cells by liposomes-containing gentamicin.

C Dees, M W Fountain, J R Taylor, R D Schultz.   

Abstract

In vitro intraphagocytic killing of Brucella abortus in bovine mononuclear leukocytes was enhanced by cationic, anionic, and neutral multilamellar liposomes-containing gentamicin. Free gentamicin not entrapped in liposomes. and liposomes without antibiotic did not enhance intraphagocytic killing of B. abortus in bovine phagocytes. In vivo killing of B. abortus in guinea pigs was also enhanced by liposomes-containing gentamicin when compared to free gentamicin. Liposomes-containing alpha tocopherol acetate failed to enhance in vivo killing of B. abortus.

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Year:  1985        PMID： 3919496     DOI： 10.1016/0165-2427(85)90120-5

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN： 0165-2427            Impact factor:   2.046


  10 in total

1.  Poly(D,L-lactide-coglycolide) particles containing gentamicin: pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice.

Authors:  M C Lecaroz; M J Blanco-Prieto; M A Campanero; H Salman; C Gamazo
Journal:  Antimicrob Agents Chemother       Date:  2007-01-12       Impact factor: 5.191

Review 2.  Liposomes as carriers of antimicrobial agents or immunomodulatory agents in the treatment of infections.

Authors:  I A Bakker-Woudenberg; A F Lokerse; M T ten Kate; P M Melissen; W van Vianen; E W van Etten
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1993       Impact factor: 3.267

3.  Effect of composition and method of preparation of liposomes on their stability and interaction with murine monocytes infected with Brucella abortus.

Authors:  A I Vitas; R Díaz; C Gamazo
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191

4.  "Haemophilus somnus," a facultative intracellular pathogen of bovine mononuclear phagocytes.

Authors:  J A Lederer; J F Brown; C J Czuprynski
Journal:  Infect Immun       Date:  1987-02       Impact factor: 3.441

5.  Survival of virulent and attenuated strains of Brucella abortus in normal and gamma interferon-activated murine peritoneal macrophages.

Authors:  S M Jones; A J Winter
Journal:  Infect Immun       Date:  1992-07       Impact factor: 3.441

Review 6.  Liposomes in drug delivery. Clinical, diagnostic and ophthalmic potential.

Authors:  G Gregoriadis; A T Florence
Journal:  Drugs       Date:  1993-01       Impact factor: 9.546

Review 7.  Liposomes in treatment of infectious diseases.

Authors:  F Emmen; G Storm
Journal:  Pharm Weekbl Sci       Date:  1987-06-19

8.  Liposome-encapsulated ampicillin against Listeria monocytogenes in vivo and in vitro.

Authors:  I A Bakker-Woudenberg; A F Lokerse; J C Vink-van den Berg; F H Roerdink
Journal:  Infection       Date:  1988       Impact factor: 3.553

9.  Successful treatment using gentamicin liposomes of Salmonella dublin infections in mice.

Authors:  J Fierer; L Hatlen; J P Lin; D Estrella; P Mihalko; A Yau-Young
Journal:  Antimicrob Agents Chemother       Date:  1990-02       Impact factor: 5.191

10.  Intracellular delivery and antibacterial activity of gentamicin encapsulated in pH-sensitive liposomes.

Authors:  P Lutwyche; C Cordeiro; D J Wiseman; M St-Louis; M Uh; M J Hope; M S Webb; B B Finlay
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191
  10 in total

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