Literature DB >> 3919144

Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule.

W T Golde, J W Kappler, J Greenstein, B Malissen, L Hood, P Marrack.   

Abstract

We show that the LFA-1 molecule on T cells does not play a role in the stimulation of T cell hybridomas by certain targets, namely antigen presented by L cell derivatives or polyvalent anti-receptor antibody. These results suggest that LFA-1 may act by binding to ligands that are not present on all cells. We hope this result will help us and others to establish the true role of LFA-1 in T cell responses.

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Year:  1985        PMID： 3919144      PMCID： PMC2187581          DOI： 10.1084/jem.161.3.635

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  13 in total

1.  T cell-mediated cytolysis: on the strength of effector-target cell interaction.

Authors:  P Bongrand; M Pierres; P Golstein
Journal:  Eur J Immunol       Date:  1983-05       Impact factor: 5.532

2.  The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas.

Authors:  J Kappler; R Kubo; K Haskins; J White; P Marrack
Journal:  Cell       Date:  1983-10       Impact factor: 41.582

3.  Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.

Authors:  S C Meuer; S F Schlossman; E L Reinherz
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

4.  Expression of H-2Dd and H-2Ld mouse major histocompatibility antigen genes in L cells after DNA-mediated gene transfer.

Authors:  D H Margulies; G A Evans; K Ozato; R D Camerini-Otero; K Tanaka; E Appella; J G Seidman
Journal:  J Immunol       Date:  1983-01       Impact factor: 5.422

5.  Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules.

Authors:  T Collins; A M Krensky; C Clayberger; W Fiers; M A Gimbrone; S J Burakoff; J S Pober
Journal:  J Immunol       Date:  1984-10       Impact factor: 5.422

6.  Lymphocyte function-associated antigen 1 (LFA-1): a surface antigen distinct from Lyt-2,3 that participates in T lymphocyte-mediated killing.

Authors:  D Davignon; E Martz; T Reynolds; K Kürzinger; T A Springer
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205

7.  The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.

Authors:  P Marrack; R Endres; R Shimonkevitz; A Zlotnik; D Dialynas; F Fitch; J Kappler
Journal:  J Exp Med       Date:  1983-10-01       Impact factor: 14.307

8.  Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1.

Authors:  I S Trowbridge; M B Omary
Journal:  J Exp Med       Date:  1981-11-01       Impact factor: 14.307

9.  The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma.

Authors:  J L Greenstein; J Kappler; P Marrack; S J Burakoff
Journal:  J Exp Med       Date:  1984-04-01       Impact factor: 14.307

10.  Clonotypic structures involved in antigen-specific human T cell function. Relationship to the T3 molecular complex.

Authors:  S C Meuer; K A Fitzgerald; R E Hussey; J C Hodgdon; S F Schlossman; E L Reinherz
Journal:  J Exp Med       Date:  1983-02-01       Impact factor: 14.307
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  5 in total

1.  Differential presentation of hepatitis B S-preS(2) particles and peptides by macrophages and B-cell like antigen-presenting cells.

Authors:  J P Scheerlinck; G Burssens; L Brys; A Michel; P Hauser; P De Baetselier
Journal:  Immunology       Date:  1991-05       Impact factor: 7.397

Review 2.  T-cell clones and T-cell receptors.

Authors:  F W Fitch
Journal:  Microbiol Rev       Date:  1986-03

3.  L3T4 but not LFA-1 participates in antigen presentation by Ak-positive L-cell transformants.

Authors:  P Naquet; B Malissen; F Bekkhoucha; S Pont; A Pierres; L Hood; M Pierres
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

4.  Analysis of HLA-DR glycoproteins by DNA-mediated gene transfer. Definition of DR2 beta gene products and antigen presentation to T cell clones from leprosy patients.

Authors:  D Wilkinson; R R de Vries; J A Madrigal; C B Lock; J P Morgenstern; J Trowsdale; D M Altmann
Journal:  J Exp Med       Date:  1988-04-01       Impact factor: 14.307

5.  TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes.

Authors:  K L Rock; E T Yeh; C F Gramm; S I Haber; H Reiser; B Benacerraf
Journal:  J Exp Med       Date:  1986-02-01       Impact factor: 14.307
  5 in total

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