Literature DB >> 3919140

Differential expression of H-2Dd and H-2Ld histocompatibility antigens.

J H Weis, C Murre.   

Abstract

To determine why the H-2Dd antigen is expressed on the surface of transfected cells at a rate several-fold higher than an analogously transfected H-2Ld molecule, we analyzed both previously described and new H-2 hybrid genes. These genes were constructed by exchanging domains between H-2 genes. Quantitative radioimmunoassay indicates that the region of the H-2Dd molecule responsible for its enhanced expression resides in the polymorphic N domain, the first domain of the mature class I molecule.

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Year:  1985        PMID： 3919140      PMCID： PMC2187564          DOI： 10.1084/jem.161.2.356

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  30 in total

1.  The major histocompatibility complex of the mouse.

Authors:  J Klein
Journal:  Science       Date:  1979-02-09       Impact factor: 47.728

2.  Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells.

Authors:  M Wigler; S Silverstein; L S Lee; A Pellicer; Y c Cheng; R Axel
Journal:  Cell       Date:  1977-05       Impact factor: 41.582

3.  Modification of the antigenic structure of the cell membrane by thymus-leukemia (TL) antibody.

Authors:  E A Boyse; E Stockert; L J Old
Journal:  Proc Natl Acad Sci U S A       Date:  1967-09       Impact factor: 11.205

4.  Absence of significant H-2 and beta 2-microglobulin mRNA expression by mouse embryonal carcinoma cells.

Authors:  D Morello; F Daniel; P Baldacci; Y Cayre; G Gachelin; P Kourilsky
Journal:  Nature       Date:  1982-03-18       Impact factor: 49.962

5.  The biology of Tla.

Authors:  E A Boyse
Journal:  Cell       Date:  1984-08       Impact factor: 41.582

6.  Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens.

Authors:  H L Ploegh; L E Cannon; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1979-05       Impact factor: 11.205

7.  An alternative hypothesis of cellular transport of lysosomal enzymes in fibroblasts. Effect of inhibitors of lysosomal enzyme endocytosis on intra- and extra-cellular lysosomal enzyme activities.

Authors:  K von Figura; E Weber
Journal:  Biochem J       Date:  1978-12-15       Impact factor: 3.857

8.  Resistance to cell-mediated cytotoxicity is correlated with reduction of H-2K gene products in AKR leukemia.

Authors:  W Schmidt; H Festenstein
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

9.  Expression of murine H-2Kb histocompatibility antigen in cells transformed with cloned H-2 genes.

Authors:  A L Mellor; L Golden; E Weiss; H Bullman; J Hurst; E Simpson; R F James; A R Townsend; P M Taylor; W Schmidt; J Ferluga; L Leben; M Santamaria; G Atfield; H Festenstein; R A Flavell
Journal:  Nature       Date:  1982-08-05       Impact factor: 49.962

10.  Antigenic modulation. Loss of TL antigen from cells exposed to TL antibody. Study of the phenomenon in vitro.

Authors:  L J Old; E Stockert; E A Boyse; J H Kim
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307
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  5 in total

Review 1.  Class I genes and molecules: an update.

Authors:  A M Lew; E P Lillehoj; E P Cowan; W L Maloy; M R van Schravendijk; J E Coligan
Journal:  Immunology       Date:  1986-01       Impact factor: 7.397

2.  Different rates of HLA class I molecule assembly which are determined by amino acid sequence in the alpha 2 domain.

Authors:  A Hill; M Takiguchi; A McMichael
Journal:  Immunogenetics       Date:  1993       Impact factor: 2.846

3.  Transcriptional regulation of HLA-A and -B: differential binding of members of the Rel and IRF families of transcription factors.

Authors:  J Girdlestone; M Isamat; D Gewert; C Milstein
Journal:  Proc Natl Acad Sci U S A       Date:  1993-12-15       Impact factor: 11.205

4.  Distinctive polymorphism at the HLA-C locus: implications for the expression of HLA-C.

Authors:  J Zemmour; P Parham
Journal:  J Exp Med       Date:  1992-10-01       Impact factor: 14.307

5.  The specific binding of peptide ligand to Ld class I major histocompatibility complex molecules determines their antigenic structure.

Authors:  W R Lie; N B Myers; J M Connolly; J Gorka; D R Lee; T H Hansen
Journal:  J Exp Med       Date:  1991-02-01       Impact factor: 14.307
  5 in total

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