Literature DB >> 3919093

Production and response to interleukin 2 in vitro and in vivo after bone marrow transplantation in mice.

V J Merluzzi, K Welte, K Last-Barney, R Mertelsmann, L Souza, T Boone, D M Savage, D Quinn, R J O'Reilly.   

Abstract

Lymphoid cells from bone marrow radiation chimeras do not produce normal levels of IL 2 but are capable of responding to IL 2 in mitogenic and cytotoxic assays in vitro. The administration of recombinant human IL 2 into host mice that have received allogeneic, H-2-compatible marrow did not enhance mortality.

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Year:  1985        PMID: 3919093

Source DB:  PubMed          Journal:  J Immunol        ISSN: 0022-1767            Impact factor:   5.422


  2 in total

1.  Association of reduced interleukin-2 production with genetic susceptibility to Pichinde virus in inbred strains of hamsters.

Authors:  K E Wright; K L Rosenthal; W E Rawls
Journal:  Arch Virol       Date:  1987       Impact factor: 2.574

2.  Toxicity and therapeutic efficacy of high-dose interleukin 2. In vivo infusion of antibody to NK-1.1 attenuates toxicity without compromising efficacy against murine leukemia.

Authors:  D J Peace; M A Cheever
Journal:  J Exp Med       Date:  1989-01-01       Impact factor: 14.307

  2 in total

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