Literature DB >> 3918873

Very large and isotypically atypical polyclonal plaque-forming cell responses in mice infected with Trypanosoma cruzi.

M R D'Imperio Lima, M Joskowicz, A Coutinho, T Kipnis, H Eisen.   

Abstract

Normal C3H/HeJ mice, acutely infected with T. cruzi, develop large numbers of splenic Ig-secreting plaque-forming cells (PFC). IgG2a, IgG2b and IgG1 PFC account for over 90% of all PFC, while the numbers of IgG3- and IgA-secreting PFC are lower than in normal animals. These effects appear to be due to both T helper-dependent regulation and to a mitogenic activity associated with the parasites themselves.

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Year:  1985        PMID： 3918873     DOI： 10.1002/eji.1830150219

Source DB:  PubMed          Journal:  Eur J Immunol        ISSN： 0014-2980            Impact factor:   5.532


  16 in total

Review 1.  Chagas' disease and the autoimmunity hypothesis.

Authors:  F Kierszenbaum
Journal:  Clin Microbiol Rev       Date:  1999-04       Impact factor: 26.132

2.  Protective effect of a T-cell-dependent immunosuppressive, B-cell-mitogenic protein (F3'EP-Si, or P90) produced by Streptococcus intermedius.

Authors:  M Lima; A Bandeira; D Portnoi; A Ribeiro; M A Chaves
Journal:  Infect Immun       Date:  1992-09       Impact factor: 3.441

3.  Chronic experimental Chagas' disease: functional syngeneic T-B-cell cooperation in vitro in the absence of an exogenous stimulus.

Authors:  C Freire-de-Lima; L M Peçanha; G A Dos Reis
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

4.  Influence of acute-phase parasite load on pathology, parasitism, and activation of the immune system at the late chronic phase of Chagas' disease.

Authors:  C R Marinho; M R D'Império Lima; M G Grisotto; J M Alvarez
Journal:  Infect Immun       Date:  1999-01       Impact factor: 3.441

5.  Pregnancy and humoral immune response in mice chronically infected by Trypanosoma cruzi.

Authors:  Y Carlier; M T Rivera; C Truyens; M Goldman; P Lambert; J Flament; D Bauwens; B Vray
Journal:  Infect Immun       Date:  1987-10       Impact factor: 3.441

6.  Glycoinositolphospholipids from Trypanosoma cruzi induce B cell hyper-responsiveness in vivo.

Authors:  A M Bilate; J O Previato; L Mendonça-Previato; L M Peçanha
Journal:  Glycoconj J       Date:  2000-10       Impact factor: 2.916

7.  Interleukin-6 (IL-6) production in mice infected with Trypanosoma cruzi: effect of its paradoxical increase by anti-IL-6 monoclonal antibody treatment on infection and acute-phase and humoral immune responses.

Authors:  C Truyens; A Angelo-Barrios; F Torrico; J Van Damme; H Heremans; Y Carlier
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

8.  BAFF mediates splenic B cell response and antibody production in experimental Chagas disease.

Authors:  Daniela A Bermejo; María C Amezcua-Vesely; Carolina L Montes; María C Merino; Ricardo C Gehrau; Hugo Cejas; Eva V Acosta-Rodríguez; Adriana Gruppi
Journal:  PLoS Negl Trop Dis       Date:  2010-05-04

9.  Chagas' disease is attenuated in mice lacking gamma delta T cells.

Authors:  E C Santos Lima; P Minoprio
Journal:  Infect Immun       Date:  1996-01       Impact factor: 3.441

10.  Strong mitogenic effect for murine B lymphocytes of an immunosuppressor substance released by Streptococcus intermedius.

Authors:  M P Arala-Chaves; A S Ribeiro; M M Santarém; A Coutinho
Journal:  Infect Immun       Date:  1986-11       Impact factor: 3.441
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