Lipids of dermatophytes II. Effect of growth condition on the lipid composition and membrane transport of Microsporum gypseum.

Supplementation of glucose-containing medium with ethanol and replacement of glucose by glycerol in the Sabouraud's growth medium of Microsporum gypseum altered the levels of total phospholipids as well as their apolar and polar head groups. The levels of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) increased under these growth conditions; also, the ratio of unsaturated/saturated phospholipid fatty acids decreased on ethanol supplementation but increased in the presence of glycerol. Steady state accumulation of labelled amino acids (glycine, lysine and aspartic acid) was affected under these conditions.