| Literature DB >> 3918227 |
M P Heyes, E S Garnett, G Coates.
Abstract
Rats were run to exhaustion on a motor driven treadmill. Apomorphine given to intact rats prolonged the time to exhaustion. Apomorphine given to 6-hydroxydopamine lesioned rats also prolonged the time to exhaustion. Intracerebroventricular 6-hydroxydopamine alone reduced the time to exhaustion. Clonidine given to these animals had no effect. We suggest that central dopaminergic activity influences rats ability to exercise.Entities:
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Year: 1985 PMID: 3918227 DOI: 10.1016/0024-3205(85)90172-9
Source DB: PubMed Journal: Life Sci ISSN: 0024-3205 Impact factor: 5.037