Literature DB >> 3917928

Efficacy of phenytoin, procainamide, and tocainide in murine genetic myotonia.

R Aichele, H Paik, A H Heller.   

Abstract

A newly described single locus mutation in the mouse, myotonia (mto), features classical myotonia with autosomal recessive inheritance. Phenytoin, procainamide, and tocainide (drugs considered effective in the human myotonias) produced dose-dependent improvement in the behavioral myotonia of mto homozygotes.

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Year:  1985        PMID: 3917928     DOI: 10.1016/0014-4886(85)90228-6

Source DB:  PubMed          Journal:  Exp Neurol        ISSN: 0014-4886            Impact factor:   5.330


  5 in total

1.  Myotonia congenita and myotonic dystrophy: surveillance and management.

Authors:  Allison Conravey; Lenay Santana-Gould
Journal:  Curr Treat Options Neurol       Date:  2010-01       Impact factor: 3.598

2.  Developmental control of the excitability of muscle: transplantation experiments on a myotonic mouse mutant.

Authors:  E M Füchtbauer; J Reininghaus; H Jockusch
Journal:  Proc Natl Acad Sci U S A       Date:  1988-06       Impact factor: 11.205

Review 3.  Skeletal Muscle Channelopathies.

Authors:  Lauren Phillips; Jaya R Trivedi
Journal:  Neurotherapeutics       Date:  2018-10       Impact factor: 7.620

Review 4.  The non-dystrophic myotonias: molecular pathogenesis, diagnosis and treatment.

Authors:  E Matthews; D Fialho; S V Tan; S L Venance; S C Cannon; D Sternberg; B Fontaine; A A Amato; R J Barohn; R C Griggs; M G Hanna
Journal:  Brain       Date:  2009-11-16       Impact factor: 13.501

5.  In vivo evaluation of antimyotonic efficacy of β-adrenergic drugs in a rat model of myotonia.

Authors:  Jean-François Desaphy; Teresa Costanza; Roberta Carbonara; Diana Conte Camerino
Journal:  Neuropharmacology       Date:  2012-09-18       Impact factor: 5.250

  5 in total

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