Literature DB >> 3917578

Insulin mediators from rat skeletal muscle have differential effects on insulin-sensitive pathways of intact adipocytes.

L Jarett, E H Wong, S L Macaulay, J A Smith.   

Abstract

The effects of partially purified insulin-generated mediators from rat skeletal muscle were compared to those of insulin on intact adipocytes. Insulin and insulin mediator stimulated both pyruvate dehydrogenase and glycogen synthase activity of intact adipocytes. In contrast, insulin stimulated glucose oxidation and 3-O-methylglucose transport, whereas insulin-generated mediators had no effect. Insulin-generated mediators cannot account for all the pleiotropic effects of insulin, especially membrane-controlled processes.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3917578     DOI： 10.1126/science.3917578

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Anti-inositolglycan antibodies selectively block some of the actions of insulin in intact BC3H1 cells.

Authors:  G Romero; G Gámez; L C Huang; K Lilley; L Luttrell
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

2.  Glucose transport and antilipolysis are differentially regulated by the polar head group of an insulin-sensitive glycophospholipid.

Authors:  K L Kelly; J M Mato; I Merida; L Jarett
Journal:  Proc Natl Acad Sci U S A       Date:  1987-09       Impact factor: 11.205

3.  Co-culture of C2C12 and 3T3-L1 preadipocyte cells alters the gene expression of calpains, caspases and heat shock proteins.

Authors:  Muthuraman Pandurangan; Dawoon Jeong; Touseef Amna; Hoa Van Ba; Inho Hwang
Journal:  In Vitro Cell Dev Biol Anim       Date:  2012-10-10       Impact factor: 2.416

4.  Insulin stimulates turnover of phosphatidylcholine in rat adipocytes.

Authors:  S L Macaulay; R G Larkins
Journal:  Mol Cell Biochem       Date:  1994-07-13       Impact factor: 3.396

5.  Insulin and phorbol ester stimulate conductive Na+ transport through a common pathway.

Authors:  M M Civan; K Peterson-Yantorno; T G O'Brien
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

6.  Inhibition of insulin receptor phosphorylation by indomethacin.

Authors:  C D Malchoff; J L Messina; V Gordon; S Tamura; J Larner
Journal:  Mol Cell Biochem       Date:  1985-11       Impact factor: 3.396
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.