Literature DB >> 3917350

Fever of unexplained origin, biochemical Cushing's disease and cerebral dysrhythmia corrected by valproate sodium.

J M López-Moreno, J A Rodríguez-Portales, D Mahana.   

Abstract

A patient with cerebral dysrhythmia and fever of unexplained origin for 2 years is described. She had elevated and nonsuppressible levels of urinary 17-hydroxycorticosteroids but no clinical features of hypercortisolism. Treatment with valproate sodium corrected all the abnormalities. It is postulated that cerebral dysrhythmia can affect the hypothalamic mechanisms of body temperature and regulation of adrenocorticotropic hormone levels.

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Year:  1985        PMID: 3917350      PMCID: PMC1346744     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  12 in total

1.  The determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma.

Authors:  R H SILBER; C C PORTER
Journal:  J Biol Chem       Date:  1954-10       Impact factor: 5.157

2.  Effect on various putative neurotransmitters on the secretion of corticotrophin-releasing hormone from the rat hypothalamus in vitro-a model of the neurotransmitters involved.

Authors:  M T Jones; E W Hillhouse; J Burden
Journal:  J Endocrinol       Date:  1976-04       Impact factor: 4.286

3.  A radioimmunoassay for measurement of thyroxine in unextracted serum.

Authors:  I J Chopra
Journal:  J Clin Endocrinol Metab       Date:  1972-06       Impact factor: 5.958

Review 4.  Drug therapy: Valproic acid.

Authors:  J Koch-Weser; T R Browne
Journal:  N Engl J Med       Date:  1980-03-20       Impact factor: 91.245

5.  Spontaneous remission of Cushing's disease. Report of a case.

Authors:  J P Hayslett; G L Cohn
Journal:  N Engl J Med       Date:  1967-04-27       Impact factor: 91.245

6.  GABA neuron systems in hypothalamus and the pituitary gland. Immunohistochemical demonstration using antibodies against glutamate decarboxylase.

Authors:  S R Vincent; T Hökfelt; J Y Wu
Journal:  Neuroendocrinology       Date:  1982-02       Impact factor: 4.914

7.  Radioimmunoassay for measurement of triiodothyronine in human serum.

Authors:  I J Chopra; D H Solomon; G N Beall
Journal:  J Clin Invest       Date:  1971-10       Impact factor: 14.808

8.  gamma-Aminobutyric acid- and benzodiazepine-binding sites in human anterior pituitary tissue.

Authors:  L Grandison; F Cavagnini; R Schmid; S C Invitti; A Guidotti
Journal:  J Clin Endocrinol Metab       Date:  1982-03       Impact factor: 5.958

9.  Effects of valproic acid, naloxone and hydrocortisone in Nelson's syndrome and cushing's disease.

Authors:  A N Elias; G Gwinup; L J Valenta
Journal:  Clin Endocrinol (Oxf)       Date:  1981-08       Impact factor: 3.478

10.  The evaluation of sodium valproate in the treatment of Nelson's syndrome.

Authors:  A Dornhorst; J S Jenkins; S W Lamberts; R R Abraham; V Wynn; U Beckford; B Gillham; M T Jones
Journal:  J Clin Endocrinol Metab       Date:  1983-05       Impact factor: 5.958

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