Literature DB >> 391695

In situ formation of antigen-antibody complexes in the mouse glomerulus.

P M Ford, I Kosatka.   

Abstract

Intravenous administration of heat-aggregated bovine serum albumin (BSA) to mice resulted in localization of micro-particulate BSA in the mesangial region of the glomerulus. Subsequent intravenous administration of rabbit anti-BSA antibody at a time when no free antigen remained in the circulation produced localization of antibody and fixation of mouse complement within the glomerulus in a pattern corresponding to that of the heat-aggregated BSA. This apparent in situ formation of immune complexes in the glomerulus is similar to that of the classical Arthus phenomenon in the skin.

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Year:  1979        PMID： 391695      PMCID： PMC1457843     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  15 in total

1.  Studies of the reticuloendothelial system (RES). I. Measurement of the phagocytic capacity of the RES in man and dog.

Authors:  M IIO; H N WAGNER; U SCHEFFEL; B JABBOUR
Journal:  J Clin Invest       Date:  1963-03       Impact factor: 14.808

2.  Experimental glomerulonephritis in the rat induced by antibodies directed against tubular antigens. V. Fixed glomerular antigens in the pathogenesis of heterologous immune complex glomerulonephritis.

Authors:  B J Van Damme; G J Fleuren; W W Bakker; R L Vernier; P J Hoedemaeker
Journal:  Lab Invest       Date:  1978-04       Impact factor: 5.662

3.  Glomerular localization and transport of aggregated proteins in mice.

Authors:  A F Michael; A J Fish; R A Good
Journal:  Lab Invest       Date:  1967-07       Impact factor: 5.662

4.  Experimental adenovirus immune complex glomerulonephritis.

Authors:  N G Wright; W I Morrison; H Thompson; H J Cornwell
Journal:  Br J Exp Pathol       Date:  1973-12

5.  Anti-basement membrane antibodies and antigen--antibody complexes in rabbits injected with mercuric chloride.

Authors:  A A Roman-Franco; M Turiello; B Albini; E Ossi; F Milgrom; G A Andres
Journal:  Clin Immunol Immunopathol       Date:  1978-04

6.  A comparative histologic and immunologic study in rabbits of induced hypersensitivity of the serum sickness type.

Authors:  F G GERMUTH
Journal:  J Exp Med       Date:  1953-02-01       Impact factor: 14.307

7.  Experimental glomerulonephritis. The pathogenesis of a laboratory model resembling the spectrum of human glomerulonephritis.

Authors:  F J DIXON; J D FELDMAN; J J VAZQUEZ
Journal:  J Exp Med       Date:  1961-05-01       Impact factor: 14.307

8.  Interstitial immune complex thyroiditis in mice: the role of autoantibody to thyroglobulin.

Authors:  J A Clagett; C B Wilson; W O Weigle
Journal:  J Exp Med       Date:  1974-12-01       Impact factor: 14.307

9.  Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes.

Authors:  S Izui; P H Lambert; G J Fournié; H Türler; P A Miescher
Journal:  J Exp Med       Date:  1977-05-01       Impact factor: 14.307

10.  EXPERIMENTAL GLOMERULONEPHRITIS. VI. THE AUTOLOGOUS PHASE OF NEPHROTOXIC SERUM NEPHRITIS.

Authors:  E R UNANUE; F J DIXON
Journal:  J Exp Med       Date:  1965-05-01       Impact factor: 14.307
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  7 in total

1.  In situ immune complex formation in the mouse glomerulus: reactivity with human IgM rheumatoid factor and the effect on subsequent immune complex deposition.

Authors:  P M Ford; I Kosatka
Journal:  Clin Exp Immunol       Date:  1983-02       Impact factor: 4.330

2.  Cationised IgM rheumatoid factor: in-vivo glomerular localization and immunoabsorptive capacity in the mouse.

Authors:  P M Ford; I Kosatka
Journal:  Clin Exp Immunol       Date:  1985-10       Impact factor: 4.330

3.  Influence of antigen charge in the pathogenicity of immune complexes in rats.

Authors:  T M Coimbra; M A Gouveia; L Ebisui; J E Barbosa; J J Lachat; I F de Carvalho
Journal:  Br J Exp Pathol       Date:  1985-10

4.  The effect of in situ formation of antigen-antibody complexes in the glomerulus on subsequent glomerular localization of passively administered immune complexes.

Authors:  P M Ford; I Kosatka
Journal:  Immunology       Date:  1980-03       Impact factor: 7.397

5.  Dynamics of mononuclear phagocyte system Fc receptor function in systemic lupus erythematosus. Relation to disease activity and circulating immune complexes.

Authors:  R P Kimberly; T M Parris; R D Inman; J S McDougal
Journal:  Clin Exp Immunol       Date:  1983-02       Impact factor: 4.330

6.  A mechanism of enhancement of immune complex deposition following in situ immune complex formation in the mouse glomerulus.

Authors:  P M Ford; I Kosatka
Journal:  Immunology       Date:  1981-07       Impact factor: 7.397

7.  The effect of protein deficiency on the development of chronic antigen-antibody complex disease in mice.

Authors:  M C Reinhardt; M Devey; M Collins; B Gregory; M W Steward
Journal:  Clin Exp Immunol       Date:  1981-06       Impact factor: 4.330
  7 in total

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