Literature DB >> 3916338

Isolation and purification of O6-alkylguanine-DNA alkyltransferase from human leukemic cells. Prevention of chloroethylnitrosourea-induced cross-links by purified enzyme.

T P Brent.   

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Year:  1985        PMID： 3916338     DOI： 10.1016/0163-7258(85)90040-3

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


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  14 in total

1.  Evidence that covalent complex formation between BCNU-treated oligonucleotides and E. coli alkyltransferases requires the O6-alkylguanine function.

Authors:  P E Gonzaga; L Harris; G P Margison; T P Brent
Journal:  Nucleic Acids Res       Date:  1990-07-11       Impact factor: 16.971

2.  Affinity purification and characterization of human O6-alkylguanine-DNA alkyltransferase complexed with BCNU-treated, synthetic oligonucleotide.

Authors:  P E Gonzaga; T P Brent
Journal:  Nucleic Acids Res       Date:  1989-08-25       Impact factor: 16.971

3.  A strategy for selective O(6)-alkylguanine-DNA alkyltransferase depletion under hypoxic conditions.

Authors:  Philip G Penketh; Krishnamurthy Shyam; Raymond P Baumann; Kimiko Ishiguro; Eric V Patridge; Rui Zhu; Alan C Sartorelli
Journal:  Chem Biol Drug Des       Date:  2012-05-23       Impact factor: 2.817

Review 4.  DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy.

Authors:  Julie L Tubbs; Anthony E Pegg; John A Tainer
Journal:  DNA Repair (Amst)       Date:  2007-05-07

5.  Characterization of the promoter region of the human O6-methylguanine-DNA methyltransferase gene.

Authors:  L C Harris; P M Potter; K Tano; S Shiota; S Mitra; T P Brent
Journal:  Nucleic Acids Res       Date:  1991-11-25       Impact factor: 16.971

6.  Repair of O-alkylpyrimidines in mammalian cells: a present consensus.

Authors:  T P Brent; M E Dolan; H Fraenkel-Conrat; J Hall; P Karran; L Laval; G P Margison; R Montesano; A E Pegg; P M Potter
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

7.  Glutathione, cell proliferation, and 1,3-bis-(2-chloroethyl)-1-nitrosourea in K562 leukemia.

Authors:  H Frischer; E J Kennedy; R Chigurupati; M Sivarajan
Journal:  J Clin Invest       Date:  1993-12       Impact factor: 14.808

8.  The effects of O6-benzylguanine and hypoxia on the cytotoxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea in nitrosourea-resistant SF-763 cells.

Authors:  A Sarkar; M E Dolan; G G Gonzalez; L J Marton; A E Pegg; D F Deen
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

9.  Interrelationship between O6-alkylguanine-DNA alkyltransferase activity and susceptibility to chloroethylnitrosoureas in several glioma cell lines.

Authors:  T Hotta; Y Saito; T Mikami; K Kurisu; K Kiya; T Uozumi; G Isowa; K Ishizaki; M Ikenaga
Journal:  J Neurooncol       Date:  1993-07       Impact factor: 4.130

10.  Formation of covalent complexes between human O6-alkylguanine-DNA alkyltransferase and BCNU-treated defined length synthetic oligodeoxynucleotides.

Authors:  T P Brent; J S Remack
Journal:  Nucleic Acids Res       Date:  1988-07-25       Impact factor: 16.971
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