Literature DB >> 391462

Hepatic first-pass metabolism in liver disease.

T F Blaschke, P C Rubin.   

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Year:  1979        PMID: 391462     DOI: 10.2165/00003088-197904060-00002

Source DB:  PubMed          Journal:  Clin Pharmacokinet        ISSN: 0312-5963            Impact factor:   6.447


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  29 in total

1.  Effect of portacaval shunt on the disposition of drugs with and without first-pass effect.

Authors:  R Gugler; P Lain; D L Azarnoff
Journal:  J Pharmacol Exp Ther       Date:  1975-12       Impact factor: 4.030

2.  Importance of "first-pass elimination" for interindividual differences in steady-state concentrations of the adrenergic beta-receptor antagonist alprenolol.

Authors:  G Alván; M Lind; B Mellström; C von Bahr
Journal:  J Pharmacokinet Biopharm       Date:  1977-06

3.  Clinical pharmacokinetics of hydrallazine.

Authors:  T Talseth
Journal:  Clin Pharmacokinet       Date:  1977 Sep-Oct       Impact factor: 6.447

4.  Effect of phenobarbitone on the disposition of lignocaine and warfarin in the dog.

Authors:  M Esquivel; T F Blaschke; G H Snidow; P J Meffin
Journal:  J Pharm Pharmacol       Date:  1978-12       Impact factor: 3.765

Review 5.  Pulmonary disease and drug kinetics.

Authors:  P du Souich; A J McLean; D Lalka; S Erill; M Gibaldi
Journal:  Clin Pharmacokinet       Date:  1978 Jul-Aug       Impact factor: 6.447

Review 6.  The hepatic artery: subservient to hepatic metabolism or guardian of normal hepatic clearance rates of humoral substances.

Authors:  W W Lautt
Journal:  Gen Pharmacol       Date:  1977

7.  Elimination of paracetamol in chronic liver disease.

Authors:  R Arnman; R Olsson
Journal:  Acta Hepatogastroenterol (Stuttg)       Date:  1978-08

8.  The influence of cirrhosis on steady-state blood concentrations of unbound propranolol after oral administration.

Authors:  A J Wood; D M Kornhauser; G R Wilkinson; D G Shand; R A Branch
Journal:  Clin Pharmacokinet       Date:  1978 Nov-Dec       Impact factor: 6.447

9.  Influence of congestive heart failure on prazosin kinetics.

Authors:  P Jaillon; P Rubin; Y G Yee; R Ball; R Kates; D Harrison; T Blaschke
Journal:  Clin Pharmacol Ther       Date:  1979-06       Impact factor: 6.875

10.  Fluorouracil therapy in patients with carcinoma of the large bowel: a pharmacokinetic comparison of various rates and routes of administration.

Authors:  N Chirstophidis; F J Vajda; I Lucas; O Drummer; W J Moon; W J Louis
Journal:  Clin Pharmacokinet       Date:  1978 Jul-Aug       Impact factor: 6.447

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  25 in total

Review 1.  Clinical pharmacokinetics in patients with liver disease.

Authors:  A J McLean; D J Morgan
Journal:  Clin Pharmacokinet       Date:  1991-07       Impact factor: 6.447

Review 2.  Drug kinetics and hepatic blood flow.

Authors:  C F George
Journal:  Clin Pharmacokinet       Date:  1979 Nov-Dec       Impact factor: 6.447

Review 3.  Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment.

Authors:  Jochen Graff; Sebastian Harder
Journal:  Clin Pharmacokinet       Date:  2013-04       Impact factor: 6.447

4.  Effects of cirrhosis and ageing on the elimination and bioavailability of ranitidine.

Authors:  C J Young; T K Daneshmend; C J Roberts
Journal:  Gut       Date:  1982-10       Impact factor: 23.059

5.  Pharmacokinetics, bioavailability and ECG response of verapamil in patients with liver cirrhosis.

Authors:  A Somogyi; M Albrecht; G Kliems; K Schäfer; M Eichelbaum
Journal:  Br J Clin Pharmacol       Date:  1981-07       Impact factor: 4.335

Review 6.  Effect of hepatic insufficiency on pharmacokinetics and drug dosing.

Authors:  R K Verbeeck; Y Horsmans
Journal:  Pharm World Sci       Date:  1998-10

7.  Treatment of liver disease with malotilate. A pharmacokinetic and pharmacodynamic phase II study in cirrhosis.

Authors:  M Bührer; J Y Le Cotonnec; M Wermeille; J Bircher
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

8.  Tianeptine and its main metabolite pharmacokinetics in chronic alcoholism and cirrhosis.

Authors:  R J Royer; M J Royer-Morrot; F Paille; D Barrucand; J Schmitt; R Defrance; C Salvadori
Journal:  Clin Pharmacokinet       Date:  1989-03       Impact factor: 6.447

9.  Pharmacokinetics and haemodynamic effects of a single oral dose of the novel ACE inhibitor spirapril in patients with chronic liver disease.

Authors:  S Krähenbühl; P Grass; A Surve; K Kutz; J Reichen
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

Review 10.  Pharmacokinetics and dosage adjustment in patients with hepatic dysfunction.

Authors:  Roger K Verbeeck
Journal:  Eur J Clin Pharmacol       Date:  2008-09-02       Impact factor: 2.953

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