| Literature DB >> 3912104 |
F Clavel, E Benhamou, R Sitruk-Ware, P Mauvais-Jarvis, R Flamant.
Abstract
The relationship between oral contraceptive use and breast cancer was investigated in 22 major epidemiological studies, which are reviewed in this paper. The overall risk ratio was never found to increase when computed among all users vs. nonusers. Risk increases were found in some studies within specific subgroups; but in general, if any risk exists, it is not much more than one. Future studies should focus specifically on women under age 25, on women before a first full-term pregnancy and, to a lesser extent, on perimenopausal women and on women who have had a benign breast disease.Entities:
Keywords: Age Factors; Biology; Breast Cancer; Cancer; Contraception; Contraceptive Agents; Contraceptive Agents, Female; Contraceptive Methods--side effects; Demographic Factors; Diseases; Family Planning; Fertility; Fertility Measurements; Literature Review; Mammary Gland Effects--history; Measurement; Neoplasms; Oral Contraceptives--side effects; Parity; Physiology; Population; Population At Risk; Population Characteristics; Population Dynamics; Reliability; Research Methodology
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Year: 1985 PMID： 3912104 DOI： 10.1016/s0010-7824(85)80002-0
Source DB: PubMed Journal: Contraception ISSN： 0010-7824 Impact factor: 3.375