Literature DB >> 3912042

Structural studies of the O-antigen polysaccharides of Klebsiella O5 and Escherichia coli O8.

P E Jansson, J Lönngren, G Widmalm, K Leontein, K Slettengren, S B Svenson, G Wrangsell, A Dell, P R Tiller.   

Abstract

The O-antigen polysaccharides of Klebsiella serotype O5 and Escherichia coli serotype O8 are serologically very similar or identical. The structures of these two polysaccharides have now been re-investigated. N.m.r. spectroscopy, chromium trioxide oxidation, hydrolysis with a specific phage enzyme, and f.a.b. mass spectrometry were the principal methods used. It is concluded that the O-antigen has the following structure, in which D-Man3Me is 3-O-methyl-D-mannose and n is approximately 10. (Formula: see text) Biosynthetic studies indicate that these antigens are synthesised by addition of D-mannopyranosyl groups to the "non-reducing" end of the mannan chain, and it seems possible that addition of a 3-O-methyl-D-mannopyranosyl group involves termination.

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Year:  1985        PMID： 3912042     DOI： 10.1016/s0008-6215(00)90412-9

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  20 in total

Review 1.  Lipopolysaccharide endotoxins.

Authors:  Christian R H Raetz; Chris Whitfield
Journal:  Annu Rev Biochem       Date:  2001-11-09       Impact factor: 23.643

2.  Identification of the methyl phosphate substituent at the non-reducing terminal mannose residue of the O-specific polysaccharides of Klebsiella pneumoniae O3, Hafnia alvei PCM 1223 and Escherichia coli O9/O9a LPS.

Authors:  Joanna Kubler-Kielb; Chris Whitfield; Ewa Katzenellenbogen; Evgeny Vinogradov
Journal:  Carbohydr Res       Date:  2011-12-03       Impact factor: 2.104

3.  Temperature-induced changes in the lipopolysaccharide of Yersinia pestis affect plasminogen activation by the pla surface protease.

Authors:  Marjo Suomalainen; Leandro Araujo Lobo; Klaus Brandenburg; Buko Lindner; Ritva Virkola; Yuriy A Knirel; Andrey P Anisimov; Otto Holst; Timo K Korhonen
Journal:  Infect Immun       Date:  2010-04-05       Impact factor: 3.441

4.  Generation of Escherichia coli O9a serotype, a subtype of E. coli O9, by transfer of the wb* gene cluster of Klebsiella O3 into E. coli via recombination.

Authors:  T Sugiyama; N Kido; Y Kato; N Koide; T Yoshida; T Yokochi
Journal:  J Bacteriol       Date:  1998-05       Impact factor: 3.490

5.  Biosynthesis of the polymannose lipopolysaccharide O-antigens from Escherichia coli serotypes O8 and O9a requires a unique combination of single- and multiple-active site mannosyltransferases.

Authors:  Laura K Greenfield; Michele R Richards; Jianjun Li; Warren W Wakarchuk; Todd L Lowary; Chris Whitfield
Journal:  J Biol Chem       Date:  2012-08-08       Impact factor: 5.157

6.  Novel adjuvant action of lipopolysaccharides that possess mannose homopolysaccharides as O-specific polysaccharides on immune responses to nonimmunogenic autoantigens in mice.

Authors:  T Yokochi; M Fukada; M Kawai; Y H Zhang; G Z Jiang; K Takahashi
Journal:  Infect Immun       Date:  1992-11       Impact factor: 3.441

7.  Prevention of renal scarring from pyelonephritis in nonhuman primates by vaccination with a synthetic Escherichia coli serotype O8 oligosaccharide-protein conjugate.

Authors:  J A Roberts; M B Kaack; G Baskin; S B Svenson
Journal:  Infect Immun       Date:  1993-12       Impact factor: 3.441

8.  Synthesis of the heteropolysaccharide O antigen of Escherichia coli O52 requires an ABC transporter: structural and genetic evidence.

Authors:  Lu Feng; Sof'ya N Senchenkova; Jinghua Yang; Alexander S Shashkov; Jiang Tao; Hongjie Guo; Jiansong Cheng; Yi Ren; Yuriy A Knirel; Peter R Reeves; Lei Wang
Journal:  J Bacteriol       Date:  2004-07       Impact factor: 3.490

9.  Domain organization of the polymerizing mannosyltransferases involved in synthesis of the Escherichia coli O8 and O9a lipopolysaccharide O-antigens.

Authors:  Laura K Greenfield; Michele R Richards; Evgeny Vinogradov; Warren W Wakarchuk; Todd L Lowary; Chris Whitfield
Journal:  J Biol Chem       Date:  2012-09-18       Impact factor: 5.157

10.  Augmented immunological activities of recombinant lipopolysaccharide possessing the mannose homopolymer as the O-specific polysaccharide.

Authors:  N Paeng; N Kido; G Schmidt; T Sugiyama; Y Kato; N Koide; T Yokochi
Journal:  Infect Immun       Date:  1996-01       Impact factor: 3.441
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