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Literature DB >> 3911140

Nortriptyline and fluphenazine in the symptomatic treatment of diabetic neuropathy. A double-blind cross-over study.

Francisco J Gomez-Perez¹, Juan A Rull, Haroldo Dies, Guillermo J Rodriguez-Rivera, Jorge Gonzalez-Barranco, Oscar Lozano-Castañeda.

Abstract

A controlled clinical trial on the efficacy of a nortriptyline-fluphenazine combination was carried out in patients with painful diabetic polyneuropathy. A visual analog scale was used to evaluate the relief of pain or paresthesia. Significant relief of both pain and paresthesia was obtained with this combination. The differences were statistically significant. Side effects were frequent but not usually severe enough to lead to cessation of these medications.

Entities: Chemical Disease Species

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Year: 1985 PMID： 3911140 DOI： 10.1016/0304-3959(85)90010-7

Source DB: PubMed Journal: Pain ISSN： 0304-3959 Impact factor: 6.961

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Cited

26 in total

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Review 5. Evidence-based guideline: Treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation.

Authors: V Bril; J England; G M Franklin; M Backonja; J Cohen; D Del Toro; E Feldman; D J Iverson; B Perkins; J W Russell; D Zochodne
Journal: Neurology Date: 2011-04-11 Impact factor: 9.910

Nortriptyline and fluphenazine in the symptomatic treatment of diabetic neuropathy. A double-blind cross-over study.

Review 1. Combination pharmacotherapy for the treatment of neuropathic pain in adults.

Review 2. National Cancer Institute-supported chemotherapy-induced peripheral neuropathy trials: outcomes and lessons.

Review 3. Antidepressants as analgesics.

Review 4. Do neuroleptic drugs still have a place in neurological therapy?

Review 5. Evidence-based guideline: Treatment of painful diabetic neuropathy: report of the American Academy of Neurology, the American Association of Neuromuscular and Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation.

6. Treatment of diabetic sensory polyneuropathy.

Review 7. Nortriptyline for neuropathic pain in adults.

Review 8. Management of painful diabetic neuropathy: guideline guidance or jungle?

9. Paroxetine for somatic pain associated with physical illness: a review.

Review 10. Pharmacotherapy of painful diabetic neuropathy.