Literature DB >> 3910538

Monoclonal antibodies to Treponema pallidum: recognition of a major polypeptide antigen.

R W Thornburg, J Morrison-Plummer, J B Baseman.   

Abstract

Hybridomas secreting monoclonal antibodies that reacted with a 45 000 dalton surface polypeptide and major immunogen of T pallidum were produced. This polypeptide was also found in T pertenue but not in T hyodysenteriae or T phagedenis biotype Reiter.

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Year:  1985        PMID： 3910538      PMCID： PMC1011746          DOI： 10.1136/sti.61.1.1

Source DB:  PubMed          Journal:  Genitourin Med        ISSN： 0266-4348


  28 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Immunity to syphilis: passive transfer in rabbits using serial doses of immune serum.

Authors:  R S Weiser; D Erickson; P L Perine; N N Pearsall
Journal:  Infect Immun       Date:  1976-05       Impact factor: 3.441

3.  Growth in Treponema hyodysenteriae in liquid medium.

Authors:  J M Kinyon; D L Harris
Journal:  Vet Rec       Date:  1974-09-07       Impact factor: 2.695

4.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

5.  A simplified method for cyanogen bromide activation of agarose for affinity chromatography.

Authors:  S C March; I Parikh; P Cuatrecasas
Journal:  Anal Biochem       Date:  1974-07       Impact factor: 3.365

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  X-ray intensifying screens greatly enhance the detection by autoradiography of the radioactive isotopes 32P and 125I.

Authors:  R Swanstrom; P R Shank
Journal:  Anal Biochem       Date:  1978-05       Impact factor: 3.365

8.  Humoral immunity in experimental syphilis. II. The relationship of neutralizing factors in immune serum to acquired resistance.

Authors:  N H Bishop; J N Miller
Journal:  J Immunol       Date:  1976-07       Impact factor: 5.422

9.  Humoral immunity in experimental syphilis. I. The demonstration of resistance conferred by passive immunization.

Authors:  N H Bishop; J N Miller
Journal:  J Immunol       Date:  1976-07       Impact factor: 5.422

10.  Parasitism by virulent Treponema pallidum of host cell surfaces.

Authors:  N S Hayes; K E Muse; A M Collier; J B Baseman
Journal:  Infect Immun       Date:  1977-07       Impact factor: 3.441
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  6 in total

1.  Cloning and expression of the major 47-kilodalton surface immunogen of Treponema pallidum in Escherichia coli.

Authors:  M V Norgard; N R Chamberlain; M A Swancutt; M S Goldberg
Journal:  Infect Immun       Date:  1986-11       Impact factor: 3.441

2.  Specific immunofluorescent staining of pathogenic treponemes with a monoclonal antibody.

Authors:  F Ito; E F Hunter; R W George; V Pope; S A Larsen
Journal:  J Clin Microbiol       Date:  1992-04       Impact factor: 5.948

3.  Development of increased serum immunoblot reactivity against a 45,000-dalton polypeptide of Treponema pallidum (Nichols) correlates with establishment of chancre immunity in syphilitic rabbits.

Authors:  R A Strugnell; W F Williams; L Drummond; J S Pedersen; B H Toh; S Faine
Journal:  Infect Immun       Date:  1986-03       Impact factor: 3.441

4.  Development and evaluation of a monoclonal antibody inhibition enzyme linked immunosorbent assay to diagnose syphilis.

Authors:  O E Ijsselmuiden; J Top; E Stolz; R V van Eijk
Journal:  Genitourin Med       Date:  1989-10

Review 5.  Polypeptides of Treponema pallidum: progress toward understanding their structural, functional, and immunologic roles. Treponema Pallidum Polypeptide Research Group.

Authors:  S J Norris
Journal:  Microbiol Rev       Date:  1993-09

6.  Isolation of a Treponema pallidum gene encoding immunodominant outer envelope protein P6, which reacts with sera from patients at different stages of syphilis.

Authors:  K M Peterson; J B Baseman; J F Alderete
Journal:  J Exp Med       Date:  1986-10-01       Impact factor: 14.307
  6 in total

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