Literature DB >> 3910327

Effect of cyclosporin A on low-dose streptozotocin diabetes in mice.

H Kolb, M Oschilewski, E Schwab, U Oschilewski, U Kiesel.   

Abstract

The effect of cyclosporin A administration on diabetes development following multiple low-dose streptozotocin treatment was determined in inbred mice. When given daily at a dose of 12 or 60 mg/kg body weight the drug induced an earlier development of hyperglycemia and led to persistently higher blood glucose levels. Enhancement of diabetes by cyclosporin A was also seen when the drug was given only after termination of treatment with streptozotocin.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 3910327

Source DB:  PubMed          Journal:  Diabetes Res        ISSN: 0265-5985


  3 in total

Review 1.  Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders.

Authors:  Diana Faulds; Karen L Goa; Paul Benfield
Journal:  Drugs       Date:  1993-06       Impact factor: 9.546

2.  The influence of cyclosporin A on the vascular permeability of the pancreatic islets and on diabetes induced by multiple low doses of streptozotocin in the mouse.

Authors:  L Jansson; S Sandler
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1988

3.  Hepatocyte growth factor intervention to reduce myocardial injury and improve cardiac function on diabetic myocardial infarction rats.

Authors:  Zaiyong Zhang; Cheng Long; Yufeng Guan; Mingcai Song
Journal:  Eur J Histochem       Date:  2020-07-30       Impact factor: 3.188

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.