Literature DB >> 3909456

A comparative trial of metronidazole v. tinidazole in the treatment of amoebic liver abscess.

A E Simjee, V Gathiram, T F Jackson, B F Khan.   

Abstract

Forty-eight patients were treated for amoebic liver abscess, 27 with metronidazole (Flagyl; Maybaker) and 21 with tinidazole (Fasigyn; Pfizer). Although 4 patients treated with tinidazole and 2 treated with metronidazole required a second course of therapy, both drugs were highly effective and resulted in rapid clinical improvement. The only side-effect was oral candidiasis, which developed in 2 patients in each drug group.

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Year:  1985        PMID: 3909456

Source DB:  PubMed          Journal:  S Afr Med J


  5 in total

Review 1.  [Therapy of tropical diseases after returning from travel].

Authors:  G D Burchard; H Sudeck
Journal:  Internist (Berl)       Date:  2003-05       Impact factor: 0.743

Review 2.  Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites.

Authors:  Vahab Ali; Tomoyoshi Nozaki
Journal:  Clin Microbiol Rev       Date:  2007-01       Impact factor: 26.132

3.  In vitro susceptibilities of Entamoeba histolytica to azithromycin, CP-63,956, erythromycin, and metronidazole.

Authors:  J I Ravdin; J Skilogiannis
Journal:  Antimicrob Agents Chemother       Date:  1989-06       Impact factor: 5.191

4.  Randomized, single-blind, placebo-controlled multicenter trial to compare the efficacy and safety of metronidazole and satranidazole in patients with amebic liver abscess.

Authors:  Jameel Muzaffar; Kaushal Madan; M P Sharma; Premashish Kar
Journal:  Dig Dis Sci       Date:  2006-11-11       Impact factor: 3.487

5.  Antiamoebic drugs for treating amoebic colitis.

Authors:  Maria Liza M Gonzales; Leonila F Dans; Juliet Sio-Aguilar
Journal:  Cochrane Database Syst Rev       Date:  2019-01-09
  5 in total

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