Literature DB >> 3909032

Recombinant interferon-alpha-2C in laryngeal papillomatosis: preliminary results of a prospective multicentre trial.

H P Zenner, W Kley, P Clarós, A Clarós, Z Labas, L P Löbe, R Pavelka, P Plath, O Ribari, D Niethammer.   

Abstract

A preparation of interferon-alpha 2C of high purity formed by recombinant DNA technology was used as adjuvant therapy following removal of laryngeal papillomas by cauterization or laser vaporization. Preliminary data on 20 patients are reported and include 11 complete and 7 partial responses. Side-effects included initial temperature elevation, but this subsided and other side-effects were uncommon. No antibodies to the interferon preparation were found in any of the patients.

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Year:  1985        PMID: 3909032     DOI: 10.1159/000226079

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  1 in total

Review 1.  Multiple metachronous skin squamous cell carcinomas and epidermodysplasia verruciformis in the head region: a human papilloma virus-associated disease.

Authors:  B P Weber; G Fierlbeck; H G Kempf
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

  1 in total

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