Literature DB >> 3907229

The application of insulin using the jet injector DG-77.

Z Resman, Z Metelko, Z Skrabalo.   

Abstract

UNLABELLED: To avoid soreness and psychic stress following insulin injections by needle and syringe, the new jet injector DG-77 was used. It is a portable percutaneous pressure device with a spring, simple to operate which can be used to apply two different types of insulin. Thirty type 1 and type 2a diabetic patients participated in the study (10 females, 20 males). Insulin was applied using a needle and the DG-77 device in the same region of the body. A standardized questionnaire was compiled concerning simplicity of application, soreness, wish to possess the device and the possibility of acquiring it. The results obtained regarding the type of application were as follows: traditional way: glycemia: at 07(00)-8.5, 10(00)-10.5, 13(00)-7.4 mmol/l; insulinemia: at 07(00)-7.5, 10(00)-20.2, 13(00)-21.0 mU/l; jet injector: glycemia - at 07(00)-8.4, 10(00)-10.4, 13(00)-8.4 mmol/l; insulinemia: at 07(00)-2.8, 10(00)-12.3, 13(00)-20.0 mU/l, which was not statistically significant; for glycemia: at 10(00), t = 0.110, p greater than 0.05, at 13(00), t = 1.88, p greater than 0.05, and for insulinemia at 10(00), t = 0.82, p greater than 0.05, and at 13(00), t = 1.23, p greater than 0.05. IN
CONCLUSION: 1) blood glucose and insulin control with the jet injector administration of insulin was equally successful as with the standard insulin application; 2) incidence of hematoma was not significant; 3) eighty-five percent of patients prefer the injector due to its simplicity of application, reduced soreness and would wish to possess the device.

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Year:  1985        PMID: 3907229     DOI: 10.1007/bf02590785

Source DB:  PubMed          Journal:  Acta Diabetol Lat        ISSN: 0001-5563


  7 in total

1.  Jet injection of insulin: comparison with conventional injection by syringe and needle.

Authors:  R Worth; J Anderson; R Taylor; K G Alberti
Journal:  Br Med J       Date:  1980-09-13

2.  Treatment of diabetes mellitus by devices.

Authors:  J S Soeldner
Journal:  Am J Med       Date:  1981-01       Impact factor: 4.965

3.  Use of jet insulin injection in diabetes mellitus therapy.

Authors:  L Cohn; R A Chez; R A Hingson; A E Szulman; M Trimmer
Journal:  Diabetes       Date:  1972-01       Impact factor: 9.461

4.  Jet injection of insulin vs the syringe-and-needle method.

Authors:  C Weller; M Linder
Journal:  JAMA       Date:  1966-03-07       Impact factor: 56.272

5.  Absorption kinetics and biologic effects of subcutaneously injected insulin preparations.

Authors:  M Berger; H J Cüppers; H Hegner; V Jörgens; P Berchtold
Journal:  Diabetes Care       Date:  1982 Mar-Apr       Impact factor: 19.112

6.  Long-term, ambulatory, subcutaneous insulin infusion versus multiple daily injections in brittle diabetic patients.

Authors:  J Barbosa; L Menth; J Eaton; D Sutherland; E F Freier; J Najarian
Journal:  Diabetes Care       Date:  1981 Mar-Apr       Impact factor: 19.112

7.  Use of the artificial B-cell (Biostator) in improving insulin therapy in unstable insulin-dependent diabetes.

Authors:  K P Ratzmann; W Bruns; B Schulz; E Zander
Journal:  Diabetes Care       Date:  1982 Jan-Feb       Impact factor: 19.112

  7 in total
  1 in total

Review 1.  Micro-scale devices for transdermal drug delivery.

Authors:  Anubhav Arora; Mark R Prausnitz; Samir Mitragotri
Journal:  Int J Pharm       Date:  2008-08-30       Impact factor: 5.875

  1 in total

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