Literature DB >> 3905317

The pharmacology and metabolism of the thiopurine drugs 6-mercaptopurine and azathioprine.

K G Van Scoik, C A Johnson, W R Porter.   

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Year:  1985        PMID： 3905317     DOI： 10.3109/03602538508991433

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN： 0360-2532            Impact factor:   4.518


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  22 in total

1.  Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine.

Authors:  T Dervieux; Y Médard; V Baudouin; A Maisin; D Zhang; F Broly; C Loirat; E Jacqz-Aigrain
Journal:  Br J Clin Pharmacol       Date:  1999-12       Impact factor: 4.335

Review 2.  Genomic medicine: genetic variation and its impact on the future of health care.

Authors:  Huntington F Willard; Misha Angrist; Geoffrey S Ginsburg
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-08-29       Impact factor: 6.237

3.  Modulation of genotoxicity of azathioprine by intracellular glutathione in hepatocytes.

Authors:  K Nagafuchi; K Miyazaki
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

4.  Plasma concentrations and organ distribution of thiopurines after oral application of azathioprine in mice.

Authors:  V Kurowski; H Iven
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

5.  Rectal bioavailability of 6-mercaptopurine in children with acute lymphoblastic leukaemia: partial avoidance of "first-pass" metabolism.

Authors:  Y Kato; T Matsushita; H Uchida; S Egi; T Yokoyama; K Mohri
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

6.  Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience.

Authors:  W R Connell; M A Kamm; J K Ritchie; J E Lennard-Jones
Journal:  Gut       Date:  1993-08       Impact factor: 23.059

7.  Simultaneous Determination of 6-Mercaptopurine and its Oxidative Metabolites in Synthetic Solutions and Human Plasma using Spectrophotometric Multivariate Calibration Methods.

Authors:  Mohammad-Hossein Sorouraddin; Mohammad-Yaser Khani; Kaveh Amini; Abdolhossein Naseri; Davoud Asgari; Mohammad-Reza Rashidi
Journal:  Bioimpacts       Date:  2011-06-09

8.  Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study.

Authors:  Kjeld Schmiegelow; Ibrahim Al-Modhwahi; Mette Klarskov Andersen; Mikael Behrendtz; Erik Forestier; Henrik Hasle; Mats Heyman; Jon Kristinsson; Jacob Nersting; Randi Nygaard; Anne Louise Svendsen; Kim Vettenranta; Richard Weinshilboum
Journal:  Blood       Date:  2009-02-17       Impact factor: 22.113

9.  6-Thioguanine nucleotide accumulation in erythrocytes during azathioprine treatment for systemic connective tissue diseases: a possible index for monitoring treatment.

Authors:  K Schmiegelow; N J Kriegbaum
Journal:  Ann Rheum Dis       Date:  1993-02       Impact factor: 19.103

10.  In vitro oxidative metabolism of 6-mercaptopurine in human liver: insights into the role of the molybdoflavoenzymes aldehyde oxidase, xanthine oxidase, and xanthine dehydrogenase.

Authors:  Kanika V Choughule; Carlo Barnaba; Carolyn A Joswig-Jones; Jeffrey P Jones
Journal:  Drug Metab Dispos       Date:  2014-05-13       Impact factor: 3.922
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