Literature DB >> 3904669

Involvement of metal particles in loosening of metal-plastic total hip prostheses.

U E Pazzaglia, L Ceciliani, M J Wilkinson, C Dell'Orbo.   

Abstract

Four loosened metal-on-plastic total hip prostheses and associated tissues were examined. Each implant showed an uncommonly high formation of metal particles produced by wear or corrosion of the femoral stem. The granulation tissue between bone and cement was characterized by macrophages containing metal particles. Histological, histochemical, and ultrastructural investigations have been performed to assess cellular reactions to ingested metal particles. Pathogenesis of loosening in these cases is discussed in relation to the role of macrophages in bone resorption.

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Year:  1985        PMID： 3904669     DOI： 10.1007/bf00454694

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN： 0344-8444


  23 in total

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  10 in total

Review 1.  The combined role of wear particles, macrophages and lymphocytes in the loosening of total joint prostheses.

Authors:  Peter A Revell
Journal:  J R Soc Interface       Date:  2008-11-06       Impact factor: 4.118

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Review 7.  Etiology of osteoarthritis: genetics and synovial joint development.

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Authors:  Huwaidha Altaf; Peter A Revell
Journal:  Inflammopharmacology       Date:  2013-05-14       Impact factor: 4.473

9.  On the inflammatory response in metal-on-metal implants.

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Authors:  Lisa K Longhofer; Alexander Chong; Nora M Strong; Paul H Wooley; Shang-You Yang
Journal:  J Orthop Translat       Date:  2016-07-14       Impact factor: 5.191
  10 in total

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