Literature DB >> 3903166

Highly reiterated non-coding sequence in the genome of Plasmodium falciparum is composed of 21 base-pair tandem repeats.

L Aslund, L Franzén, G Westin, T Persson, H Wigzell, U Pettersson.   

Abstract

Clones containing highly reiterated DNA sequences were isolated from a Plasmodium falciparum genomic library. One clone, Rep2, was selected for further characterization by nucleotide sequence analysis. The results revealed that the insert of this clone is composed of tandemly arranged 21 base-pair imperfect repeats. These repeats are estimated to comprise approximately 1% of the P. falciparum genome and there are 10(4) to 2 X 10(5) copies, depending on the genome size estimate used for calculation. Moreover, the repeats are organized in clusters and do not appear to be transcribed in non-synchronized P. falciparum cultures.

Entities:  

Mesh:

Substances:

Year:  1985        PMID: 3903166     DOI: 10.1016/0022-2836(85)90067-1

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  15 in total

Review 1.  Repetitive elements in genomes of parasitic protozoa.

Authors:  Bill Wickstead; Klaus Ersfeld; Keith Gull
Journal:  Microbiol Mol Biol Rev       Date:  2003-09       Impact factor: 11.056

2.  Organization of subtelomeric repeats in Plasmodium berghei.

Authors:  E Dore; T Pace; M Ponzi; L Picci; C Frontali
Journal:  Mol Cell Biol       Date:  1990-05       Impact factor: 4.272

3.  Diagnosis of Plasmodium falciparum infection by spot hybridization assay: specificity, sensitivity, and field applicability.

Authors:  M Holmberg; A Björkman; L Franzén; L Aslund; M Lebbad; U Pettersson; H Wigzell
Journal:  Bull World Health Organ       Date:  1986       Impact factor: 9.408

4.  Comparison of genomic, plasmid, synthetic, and combined DNA probes for detecting Plasmodium falciparum DNA.

Authors:  G L McLaughlin; W E Collins; G H Campbell
Journal:  J Clin Microbiol       Date:  1987-05       Impact factor: 5.948

5.  DNA hybridization for assessment of response of Plasmodium falciparum to chloroquine therapy.

Authors:  G L McLaughlin; P Deloron; A Y Huong; C Sezibera; G H Campbell
Journal:  J Clin Microbiol       Date:  1988-09       Impact factor: 5.948

6.  A genetic screen for improved plasmid segregation reveals a role for Rep20 in the interaction of Plasmodium falciparum chromosomes.

Authors:  Rebecca A O'Donnell; Lúcio H Freitas-Junior; Peter R Preiser; Donald H Williamson; Manoj Duraisingh; Terry F McElwain; Artur Scherf; Alan F Cowman; Brendan S Crabb
Journal:  EMBO J       Date:  2002-03-01       Impact factor: 11.598

Review 7.  Genome plasticity in Plasmodium.

Authors:  C Frontali
Journal:  Genetica       Date:  1994       Impact factor: 1.082

8.  DNA organization and polymorphism of a wild-type Drosophila telomere region.

Authors:  M F Walter; C Jang; B Kasravi; J Donath; B M Mechler; J M Mason; H Biessmann
Journal:  Chromosoma       Date:  1995-12       Impact factor: 4.316

9.  Cloning and characterisation of a repetitive DNA sequence from Theileria mutans: application as a species-specific probe.

Authors:  R P Bishop; B K Sohanpal; S P Morzaria
Journal:  Parasitol Res       Date:  1994       Impact factor: 2.289

10.  The use of DNA probes for malaria diagnosis: memorandum from a WHO meeting.

Authors: 
Journal:  Bull World Health Organ       Date:  1986       Impact factor: 9.408

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.