Literature DB >> 3903107

Microbial side-chain degradation of sterols.

K Kieslich.   

Abstract

Apart from the broadly used diosgenin and some further natural compounds sterols gained an increasing importance as raw material for the synthesis of steroid drugs. Parallel to the elucidation of the pathways of the enzymatic degradation of sterols technical processes were developed for a specific degradation of the side-chain to useful primary products. A review is given on the present state of this field and the trends to further improvements.

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Year:  1985        PMID： 3903107     DOI： 10.1002/jobm.3620250713

Source DB:  PubMed          Journal:  J Basic Microbiol        ISSN： 0233-111X            Impact factor:   2.281


  28 in total

1.  Progesterone side-chain degradation by some species of Aspergillus flavus group.

Authors:  M E Mostafa; A A Zohri
Journal:  Folia Microbiol (Praha)       Date:  2000       Impact factor: 2.099

2.  Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism.

Authors:  Suzanne T Thomas; Brian C VanderVen; David R Sherman; David G Russell; Nicole S Sampson
Journal:  J Biol Chem       Date:  2011-11-01       Impact factor: 5.157

3.  Bioconversion of phytosterols to androstanes by mycobacteria growing on sugar cane mud.

Authors:  C Pérez; A Falero; B R Hung; S Tirado; Y Balcinde
Journal:  J Ind Microbiol Biotechnol       Date:  2005-03-15       Impact factor: 3.346

4.  A very efficient bioconversion of soybean phytosterols mixtures to androstanes by mycobacteria.

Authors:  C Pérez; A Falero; H Luu Duc; Y Balcinde; B R Hung
Journal:  J Ind Microbiol Biotechnol       Date:  2006-06-07       Impact factor: 3.346

5.  Two new 17 α-hydroxyprogesterone transformation products fromNocardia DSM 43298.

Authors:  S Choudhry; S Halos; D Krischenowski; G Schmeda-Hirschmann
Journal:  World J Microbiol Biotechnol       Date:  1993-01       Impact factor: 3.312

6.  Testosterone-regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni.

Authors:  E Möbus; M Jahn; R Schmid; D Jahn; E Maser
Journal:  J Bacteriol       Date:  1997-09       Impact factor: 3.490

7.  Microbial transformations and bioconversions. Patents and literature.

Authors:  R J Linhardt
Journal:  Appl Biochem Biotechnol       Date:  1986-12       Impact factor: 2.926

8.  Cholest-4-en-3-one-delta 1-dehydrogenase, a flavoprotein catalyzing the second step in anoxic cholesterol metabolism.

Authors:  Yin-Ru Chiang; Wael Ismail; Sébastien Gallien; Dimitri Heintz; Alain Van Dorsselaer; Georg Fuchs
Journal:  Appl Environ Microbiol       Date:  2007-11-09       Impact factor: 4.792

9.  Anaerobic and aerobic cleavage of the steroid core ring structure by Steroidobacter denitrificans.

Authors:  Po-Hsiang Wang; Yann-Lii Leu; Wael Ismail; Sen-Lin Tang; Ching-Yen Tsai; Hsing-Ju Chen; Ann-Tee Kao; Yin-Ru Chiang
Journal:  J Lipid Res       Date:  2013-03-04       Impact factor: 5.922

10.  The essential function of genes for a hydratase and an aldehyde dehydrogenase for growth of Pseudomonas sp. strain Chol1 with the steroid compound cholate indicates an aldolytic reaction step for deacetylation of the side chain.

Authors:  Johannes Holert; Nina Jagmann; Bodo Philipp
Journal:  J Bacteriol       Date:  2013-05-24       Impact factor: 3.490
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