Effects of insulin on the metabolism of acetate, beta-hydroxybutyrate and triglycerides by the bovine mammary gland.

The effect of insulin on net metabolism of acetate, beta-hydroxybutyrate, glucose and triglycerides by the bovine mammary gland was determined using the glucose clamp technique. Elevation of insulin concentrations in plasma by 50 microU/ml was not associated with significant changes in venoarterial concentration differences and extraction ratios ((A-V)/A). Insulin does not appear to alter the metabolism of acetate, beta-hydroxybutyrate, glucose and triglycerides by direct effects on the mammary gland.