Literature DB >> 3897067

Antigen-reactivity pattern of T-cell hybridomas from Mycobacterium bovis BCG-infected mice.

I Müller, S H Kaufmann.   

Abstract

Lymph node cells from mice infected with live Mycobacterium bovis BCG were fused with BW5147 cells after short-term culturing in vitro. Both mycobacterium- and self-reactive T-cell hybridomas were identified. Some T-cell hybridoma clones displayed dual reactivity to self and to self plus mycobacterial antigen but did so to a different degree, indicating that infection with mycobacteria stimulates autoreactive immune responses.

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Year:  1985        PMID： 3897067      PMCID： PMC261292          DOI： 10.1128/iai.49.3.838-840.1985

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  9 in total

1.  T-cell receptors generated via mutations are specific for various major histocompatibility antigens.

Authors:  A A Augustin; G K Sim
Journal:  Cell       Date:  1984-11       Impact factor: 41.582

2.  Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli.

Authors:  D I Beller; J M Kiely; E R Unanue
Journal:  J Immunol       Date:  1980-03       Impact factor: 5.422

3.  An IL 2-secreting T cell hybridoma that responds to a self class I histocompatibility antigen in the H-2D region.

Authors:  R O Endres; P Marrack; J W Kappler
Journal:  J Immunol       Date:  1983-10       Impact factor: 5.422

4.  Biological functions of t cell lines with specificity for the intracellular bacterium Listeria monocytogenes in vitro and in vivo.

Authors:  S H Kaufmann; H Hahn
Journal:  J Exp Med       Date:  1982-06-01       Impact factor: 14.307

5.  Bidirectional amplification of macrophage-lymphocyte interactions: enhanced lymphocyte activation factor production by activated adherent mouse peritoneal cells.

Authors:  M S Meltzer; J J Oppenheim
Journal:  J Immunol       Date:  1977-01       Impact factor: 5.422

6.  Production of autoreactive I region-restricted T cell hybridomas.

Authors:  L H Glimcher; E M Shevach
Journal:  J Exp Med       Date:  1982-08-01       Impact factor: 14.307

7.  The role of Ia molecules in the activation of T lymphocytes. III. Antigen-specific, Ia-restricted, interleukin 2-producing T cell hybridomas with detectable affinity for the restricting I-A molecule.

Authors:  K L Rock; B Benacerraf
Journal:  J Exp Med       Date:  1983-01-01       Impact factor: 14.307

8.  Surface properties of bacillus Calmette-Guérin-activated mouse macrophages. Reduced expression of mannose-specific endocytosis, Fc receptors, and antigen F4/80 accompanies induction of Ia.

Authors:  R A Ezekowitz; J Austyn; P D Stahl; S Gordon
Journal:  J Exp Med       Date:  1981-07-01       Impact factor: 14.307

9.  Antigen-inducible, H-2-restricted, interleukin-2-producing T cell hybridomas. Lack of independent antigen and H-2 recognition.

Authors:  J W Kappler; B Skidmore; J White; P Marrack
Journal:  J Exp Med       Date:  1981-05-01       Impact factor: 14.307
  9 in total

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