| Literature DB >> 3897016 |
R Stanhope, N A Abdulwahid, J Adams, H S Jacobs, C G Brook.
Abstract
The induction of puberty by the administration of subcutaneous 15-micrograms pulses of gonadotrophin-releasing hormone (GnRH) every 90 min during day and night is described in two patients. Too rapid an induction of puberty occurred in one patient while initial progress in the other ceased after the development of pituitary desensitisation. We have attributed these results to the use of GnRH pulses in too high amplitude, and we suggest a more appropriate dose regimen.Entities:
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Year: 1985 PMID： 3897016 DOI： 10.1159/000180075
Source DB: PubMed Journal: Horm Res ISSN： 0301-0163