Literature DB >> 3895910

Thyroxine supplementation. Method for the prevention of clinical hypothyroidism.

J Tibaldi, U S Barzel.   

Abstract

Elevation in the blood level of thyroid-stimulating hormone (thyrotropin) is the earliest and most sensitive manifestation of thyroidal failure, and is detectable in clinically healthy and apparently euthyroid persons. Oral thyroxine supplementation designed to titrate thyrotropin back to normal levels, and readjustment of the supplementary dose as failure of the gland progresses and thyrotropin level rises again, may prevent the emergence of clinical hypothyroidism.

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Year:  1985        PMID: 3895910     DOI: 10.1016/0002-9343(85)90015-4

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  3 in total

Review 1.  Periodic health examination, 1990 update: 1. Early detection of hyperthyroidism and hypothyroidism in adults and screening of newborns for congenital hypothyroidism. Canadian Task Force on the Periodic Health Examination.

Authors: 
Journal:  CMAJ       Date:  1990-05-01       Impact factor: 8.262

2.  Normal thyroxine and elevated thyrotropin concentrations: evolving hypothyroidism or persistent euthyroidism with reset thyrostat.

Authors:  U M Kabadi; R Cech
Journal:  J Endocrinol Invest       Date:  1997-06       Impact factor: 4.256

3.  Thyroid antoantibodies and the response to thyrotropin releasing hormone in patients with subclinical hypothyroidism.

Authors:  O A Mojiminiyi; V Rege; J Bolodeoku; A H Wilcox; J L Barron
Journal:  J Clin Pathol       Date:  1995-05       Impact factor: 3.411

  3 in total

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