| Literature DB >> 3895580 |
L S Queiroz, H Santo Neto, M T Assakura, A P Reichl, F R Mandelbaum.
Abstract
Haemorrhagic factor HF2 and bothropasin, two metalloproteins isolated from the venom of Bothrops jararaca, caused haemorrhage followed by myonecrosis and arterial necrosis after i.m. injection in mice. The effects of HF2 were qualitatively similar to those of bothropasin and crude B. jararaca venom, but its potency was about 20 times higher. The haemorrhagic and necrotizing actions of these components are unrelated to their proteolytic activity on casein.Entities:
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Year: 1985 PMID： 3895580 DOI： 10.1016/0041-0101(85)90158-8
Source DB: PubMed Journal: Toxicon ISSN： 0041-0101 Impact factor: 3.033