| Literature DB >> 3894805 |
D M Kamat, R Gopal, S H Advani, C N Nair, A Kumar, T Saikia, J J Nadkarni, J S Nadkarni.
Abstract
Leukemic cells from 124 acute lymphoblastic leukemia (ALL) and 31 chronic lymphatic leukemia (CLL) were examined for sheep erythrocyte receptor (E), surface immunoglobulin (SIg) and their reactivity with a panel of monoclonal antibodies recognizing specific surface antigens including pan-T, Common ALL and Ia antigens. In acute lymphatic leukemia, 33% of patients reveal T-cell receptor associated with higher age group, mediastinal mass and high WBC count. Common ALL was predominant between 2 and 9-yr age group. Among chronic lymphatic leukemia, 2 patients were found to be T-CLL while 29 revealed presence of SIg. Ia antigen was detected in 44.4% of ALL and 64% fo CLL patients. The pattern of surface marker observed in our series may be related to our life style, socio-economic and environmental factors.Entities:
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Year: 1985 PMID： 3894805 DOI： 10.1016/0145-2126(85)90315-7
Source DB: PubMed Journal: Leuk Res ISSN： 0145-2126 Impact factor: 3.156