Literature DB >> 389309

Terminal deoxynucleotidyl transferase as a hematopoietic cell marker.

F J Bollum.   

Abstract

Terminal deoxynucleotidyl transferase (TdT) is an intracellular protein characteristic of certain primitive lymphocytes in normal thymus and bone marrow. It can be detected by enzyme assay or immunocytochemical staining. High levels of enzyme and increased numbers of TdT+ cells are found in some lymphoblastic leukemias and lymphomas. Analysis for TdT thus provides a useful adjunct in the differential diagnosis of leukemia.

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Year:  1979        PMID： 389309

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  64 in total

1.  Biphenotypic, bilineal, ambiguous or mixed lineage: strange leukemias!

Authors:  Marie C Béné
Journal:  Haematologica       Date:  2009-07       Impact factor: 9.941

2.  Biphenotypic leukaemia: a case of mixed T lymphoblastic and myeloblastic leukaemia.

Authors:  M A Morgan; C S Scott; J Tavares de Castro; H J Limbert; N Polli; D Catovsky; R D Pyrah; B E Roberts
Journal:  J Clin Pathol       Date:  1985-05       Impact factor: 3.411

3.  Establishment of the DU.528 human lymphohemopoietic stem cell line.

Authors:  J Kurtzberg; S H Bigner; M S Hershfield
Journal:  J Exp Med       Date:  1985-11-01       Impact factor: 14.307

Review 4.  Immunocytochemical method for the detection of terminal deoxynucleotidyl transferase in acute leukemia.

Authors:  A D Ho; V Helmstädter; W Hunstein
Journal:  Klin Wochenschr       Date:  1982-05-03

5.  Molecular cloning of human terminal deoxynucleotidyltransferase.

Authors:  R C Peterson; L C Cheung; R J Mattaliano; L M Chang; F J Bollum
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

6.  LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes.

Authors:  K Lo; N R Landau; S T Smale
Journal:  Mol Cell Biol       Date:  1991-10       Impact factor: 4.272

7.  Leukemic cell differentiation in childhood leukemias. Analysis by enzyme markers.

Authors:  G Gaedicke; H G Drexler
Journal:  Eur J Pediatr       Date:  1984-08       Impact factor: 3.183

8.  Marker profiles of human leukemia and lymphoma cell lines.

Authors:  J Minowada; H Koshiba; K Sagawa; I Kubonishi; M S Lok; E Tatsumi; T Han; B I Srivastava; T Ohnuma
Journal:  J Cancer Res Clin Oncol       Date:  1981       Impact factor: 4.553

9.  Malignant lymphomas: cell surface markers and advances in classification.

Authors:  J A Strauchen
Journal:  West J Med       Date:  1981-10

10.  Characterization of early lymphoid precursor cells in the human fetus using monoclonal antibodies and anti-terminal deoxynucleotidyl transferase.

Authors:  G E Asma; R L van den Bergh; J M Vossen
Journal:  Clin Exp Immunol       Date:  1986-05       Impact factor: 4.330
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