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Literature DB >> 3892571

Thiopyronine and 8-methoxypsoralen sensitized photodynamic effect on DNA synthesis in yeast.

Abstract

The synthesis of DNA in growing yeast cells was investigated after photodynamic treatment of the cells with thiopyronine (TP) and visible light or with 8-methoxypsoralen (8-MOP) and UVA light. DNA synthesis was inhibited after photodynamic treatment with 8-MOP but not after photodynamic treatment with TP. This result is further evidence that the photodynamic effect with TP does not attack nuclear DNA in eucaryotic cells.

Entities: Chemical Species

Mesh：

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Year: 1985 PMID： 3892571 DOI： 10.1007/bf01229822

Source DB: PubMed Journal: Radiat Environ Biophys ISSN： 0301-634X Impact factor: 1.925

12 in total

Review 1. Photochemistry and photobiology of psoralens.

Authors: P S Song; K J Tapley
Journal: Photochem Photobiol Date: 1979-06 Impact factor: 3.421

Review 2. Selected topics in photochemistry of nucleic acids. Recent results and perspectives.

Authors: G Löber; L Kittler
Journal: Photochem Photobiol Date: 1977-02 Impact factor: 3.421

3. Thiopyronine-sensitized photodynamic inactivation of RNA synthesis in vitro.

Authors: A Micheler; S Nishiyama-Watanabe
Journal: Int J Radiat Biol Relat Stud Phys Chem Med Date: 1977-01

4. Specific DNA-labelling by exogenous thymidine-5'-monophosphate in Saccharomyces cerevisiae.

Authors: W W Fäth; M Brendel
Journal: Mol Gen Genet Date: 1974

5. Complex formation and energy transfer from photoexcited thiopyronine to deoxyribonucleic acid.

Authors: S Lalitha; A Haug
Journal: Biochemistry Date: 1972-04-25 Impact factor: 3.162

Review 6. Psoralen photochemistry.

Authors: B J Parsons
Journal: Photochem Photobiol Date: 1980-12 Impact factor: 3.421

1. Investigation of some antimicrobial procedures on the in vitro development of early murine embryos aimed toward developing methods for the disinfection of mammalian embryos prior to transfer.

Authors: A Bielanski; W C Hare
Journal: J In Vitro Fert Embryo Transf Date: 1991-02

1 in total

Thiopyronine and 8-methoxypsoralen sensitized photodynamic effect on DNA synthesis in yeast.

Review 1. Photochemistry and photobiology of psoralens.

Review 2. Selected topics in photochemistry of nucleic acids. Recent results and perspectives.

3. Thiopyronine-sensitized photodynamic inactivation of RNA synthesis in vitro.

4. Specific DNA-labelling by exogenous thymidine-5'-monophosphate in Saccharomyces cerevisiae.

5. Complex formation and energy transfer from photoexcited thiopyronine to deoxyribonucleic acid.

Review 6. Psoralen photochemistry.

7. Sedimentation analysis of DNA photooxidized in the presence of thiopyronine.

8. In vivo production of DNA single-strand breaks by photodynamic action.

9. Photodynamic action of thiopyronine on polyribosomes and cell-free protein synthesis in yeast.

10. Thiopyronine sensitized photodynamic effect on ribosome synthesis and ribosome content in Saccharomyces cells.

1. Investigation of some antimicrobial procedures on the in vitro development of early murine embryos aimed toward developing methods for the disinfection of mammalian embryos prior to transfer.