Literature DB >> 3892021

Comparative deposition of inhaled aerosols in experimental animals and humans: a review.

R B Schlesinger.   

Abstract

The biological effects of inhaled aerosols are often related to their site(s) of deposition within the respiratory tract. However, deposition patterns may differ between humans and those experimental animals commonly used in inhalation toxicology studies, making cross-species risk extrapolations difficult. This paper reviews the factors that control deposition and synthesizes much of the available data on comparative regional deposition.

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Year:  1985        PMID： 3892021     DOI： 10.1080/15287398509530647

Source DB:  PubMed          Journal:  J Toxicol Environ Health        ISSN： 0098-4108


  44 in total

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2.  Impact of relative humidity and collection media on mycobacteriophage D29 aerosol.

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Review 3.  Progress on adenovirus-vectored universal influenza vaccines.

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Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

4.  Small molecule targeting of the STAT5/6 Src homology 2 (SH2) domains to inhibit allergic airway disease.

Authors:  J Morgan Knight; Pijus Mandal; Pietro Morlacchi; Garbo Mak; Evan Li; Matthew Madison; Cameron Landers; Brandon Saxton; Ed Felix; Brian Gilbert; Joel Sederstrom; Atul Varadhachary; Melissa M Singh; Dev Chatterjee; David B Corry; John S McMurray
Journal:  J Biol Chem       Date:  2018-05-08       Impact factor: 5.157

5.  The toxicity of microcystin LR in mice following 7 days of inhalation exposure.

Authors:  Janet M Benson; Julie A Hutt; Kathleen Rein; Susan E Boggs; Edward B Barr; Lora E Fleming
Journal:  Toxicon       Date:  2005-05       Impact factor: 3.033

6.  Fate of aerosolized recombinant DNA-produced alpha 1-antitrypsin: use of the epithelial surface of the lower respiratory tract to administer proteins of therapeutic importance.

Authors:  R C Hubbard; M A Casolaro; M Mitchell; S E Sellers; F Arabia; M A Matthay; R G Crystal
Journal:  Proc Natl Acad Sci U S A       Date:  1989-01       Impact factor: 11.205

7.  International Society for the Advancement of Cytometry cell sorter biosafety standards.

Authors:  Kevin L Holmes; Benjamin Fontes; Philip Hogarth; Richard Konz; Simon Monard; Charles H Pletcher; Robert B Wadley; Ingrid Schmid; Stephen P Perfetto
Journal:  Cytometry A       Date:  2014-03-13       Impact factor: 4.355

8.  Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function.

Authors:  S Vamsee Raju; Patricia L Jackson; Clifford A Courville; Carmel M McNicholas; Peter A Sloane; Gina Sabbatini; Sherry Tidwell; Li Ping Tang; Bo Liu; James A Fortenberry; Caleb W Jones; Jeremy A Boydston; J P Clancy; Larry E Bowen; Frank J Accurso; J Edwin Blalock; Mark T Dransfield; Steven M Rowe
Journal:  Am J Respir Crit Care Med       Date:  2013-12-01       Impact factor: 21.405

Review 9.  Dosimetry considerations for animal aerosol inhalation studies.

Authors:  Robert F Phalen; Loyda B Mendez
Journal:  Biomarkers       Date:  2009-07       Impact factor: 2.658

10.  MegaRibavirin aerosol for the treatment of influenza A virus infections in mice.

Authors:  Brian E Gilbert; Matthew T McLeay
Journal:  Antiviral Res       Date:  2008-02-04       Impact factor: 5.970
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