Literature DB >> 389175

Intrathecal serotherapy in neonatal tetanus: a controlled trial.

M R Sedaghatian.   

Abstract

60 infants with neonatal tetanus were treated at random either by 40 000 units of equine tetanus antitoxin (TAT), intravenously and intramuscularly, or by 40 000 units TAT, IV and IM, plus 150 units of human tetanus immune globulin TIG) intrathecally. There were 30 infants in each treatment group. Babies were similar in age, sex, weight, incubation period, temperature, and signs and symptoms on arrival at the hospital. The mortality rate, days in hospital and days of sedation were not significantly different in the two groups.

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Year:  1979        PMID: 389175      PMCID: PMC1545797          DOI: 10.1136/adc.54.8.623

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  9 in total

1.  Value of a large dose of antitoxin in clinical tetanus.

Authors:  A BROWN; S D MOHAMED; R D MONTGOMERY; P ARMITAGE; D R LAURENCE
Journal:  Lancet       Date:  1960-07-30       Impact factor: 79.321

2.  Cause of death in tetanus neonatorum: study of 233 cases with 54 necropsies.

Authors:  R Salimpour
Journal:  Arch Dis Child       Date:  1977-07       Impact factor: 3.791

3.  Tetanus neonatorum in West Malaysia.

Authors:  S T Chen
Journal:  J Trop Med Hyg       Date:  1974-09

4.  Double-blind trial of equine antitoxin and human immune globulin in tetanus neonatorum.

Authors:  G H McCracken; D L Dowell; F N Marshall
Journal:  Lancet       Date:  1971-06-05       Impact factor: 79.321

5.  Intrathecal serotherapy of tetanus. I. Explanation of complications. II. Comparison of intrathecal tetanus immune globulin and tetanus antitoxin.

Authors:  I Ildirim
Journal:  Turk J Pediatr       Date:  1974-07       Impact factor: 0.552

6.  Tetanus neonatorum in Iran. Notes on etiology, manifestations and therapy.

Authors:  A Nourmand; A Ghavami; M Ziai; A C Tahernia
Journal:  Clin Pediatr (Phila)       Date:  1970-10       Impact factor: 1.168

7.  A new treatment for neonatal tetanus. Antitetanic serum and prednisolone given together intrathecally.

Authors:  I Ildirim
Journal:  Turk J Pediatr       Date:  1967-07       Impact factor: 0.552

8.  The fourth international conference on tetanus, Dakar, Sénégal, 1975.

Authors:  W Furste
Journal:  J Trauma       Date:  1976-09

9.  Role of tetanus antitoxin in the treatment of tetanus in children.

Authors:  V B Athavale; P N Pai
Journal:  J Pediatr       Date:  1966-02       Impact factor: 4.406

  9 in total

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