Literature DB >> 3890571

Induction and isolation of artemisinine-resistant mutants of Plasmodium falciparum.

J Inselburg.   

Abstract

Five artemisinine-resistant mutants of Plasmodium falciparum have been isolated from a cloned parent following mutagenic treatment with N-methyl-N'-nitronitrosoguanidine. This observation may influence the strategy of the use of artemisinine or its derivatives. Mutant isolation should prove useful in the study of drug resistance to other antimalarials.

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Year:  1985        PMID： 3890571     DOI： 10.4269/ajtmh.1985.34.417

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  14 in total

1.  Genetic predisposition favors the acquisition of stable artemisinin resistance in malaria parasites.

Authors:  Dorothee Beez; Cecilia P Sanchez; Wilfred D Stein; Michael Lanzer
Journal:  Antimicrob Agents Chemother       Date:  2010-11-01       Impact factor: 5.191

2.  Role of pfmdr1 amplification and expression in induction of resistance to artemisinin derivatives in Plasmodium falciparum.

Authors:  Marina Chavchich; Lucia Gerena; Jennifer Peters; Nanhua Chen; Qin Cheng; Dennis E Kyle
Journal:  Antimicrob Agents Chemother       Date:  2010-03-29       Impact factor: 5.191

3.  Plasmodium falciparum: development of a transgenic line for screening antimalarials using firefly luciferase as the reporter.

Authors:  Long Cui; Jun Miao; Jiaxu Wang; Qianjun Li; Liwang Cui
Journal:  Exp Parasitol       Date:  2008-05-29       Impact factor: 2.011

Review 4.  Origin and Spread of Evolving Artemisinin-Resistant Plasmodium falciparum Malarial Parasites in Southeast Asia.

Authors:  Matthew R Hassett; Paul D Roepe
Journal:  Am J Trop Med Hyg       Date:  2019-12       Impact factor: 2.345

5.  Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum.

Authors:  Long Cui; Zenglei Wang; Jun Miao; Miao Miao; Ramesh Chandra; Hongying Jiang; Xin-zhuan Su; Liwang Cui
Journal:  Mol Microbiol       Date:  2012-08-06       Impact factor: 3.501

6.  Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine.

Authors:  A Brockman; R N Price; M van Vugt; D G Heppner; D Walsh; P Sookto; T Wimonwattrawatee; S Looareesuwan; N J White; F Nosten
Journal:  Trans R Soc Trop Med Hyg       Date:  2000 Sep-Oct       Impact factor: 2.184

7.  Phenotypic and genotypic analysis of in vitro-selected artemisinin-resistant progeny of Plasmodium falciparum.

Authors:  Matthew S Tucker; Tina Mutka; Kansas Sparks; Janus Patel; Dennis E Kyle
Journal:  Antimicrob Agents Chemother       Date:  2011-11-14       Impact factor: 5.191

Review 8.  Artemisia annua L.: a source of novel antimalarial drugs.

Authors:  H J Woerdenbag; C B Lugt; N Pras
Journal:  Pharm Weekbl Sci       Date:  1990-10-19

9.  Artemisinin resistance in Plasmodium falciparum: A process linked to dormancy?

Authors:  Qin Cheng; Dennis E Kyle; Michelle L Gatton
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-01-27       Impact factor: 4.077

10.  Selection and reversal of Plasmodium berghei resistance in the mouse model following repeated high doses of artemether.

Authors:  Shu-Hua Xiao; Jun-Min Yao; Jürg Utzinger; Yue Cai; Jacques Chollet; Marcel Tanner
Journal:  Parasitol Res       Date:  2003-12-16       Impact factor: 2.289
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