Literature DB >> 3889600

A mutagen precursor in Chinese cabbage, indole-3-acetonitrile, which becomes mutagenic on nitrite treatment.

K Wakabayashi, M Nagao, M Ochiai, T Tahira, Z Yamaizumi, T Sugimura.   

Abstract

After treatment with nitrite, Chinese cabbage showed direct-acting mutagenicity on Salmonella typhimurium TA100 inducing 3100 revertants per g. One of the mutagen precursors that became mutagenic after nitrite treatment was isolated, and identified as indole-3-acetonitrile. After treatment with nitrite, 1 mg of indole-3-acetonitrile induced 17 400 revertants of TA100 and 21 000 revertants of TA98 without S9 mix.

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Year:  1985        PMID: 3889600     DOI: 10.1016/0165-7992(85)90098-3

Source DB:  PubMed          Journal:  Mutat Res        ISSN: 0027-5107            Impact factor:   2.433


  3 in total

1.  In-vitro testing and the carcinogenic potential of several nitrosated indole compounds.

Authors:  H G Tiedink; L H de Haan; W M Jongen; J H Koeman
Journal:  Cell Biol Toxicol       Date:  1991-10       Impact factor: 6.691

Review 2.  Past, present, and future of mutagens in cooked foods.

Authors:  T Sugimura
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

3.  Mutagenicity arising from boiled rice on treatment with nitrous acid.

Authors:  H Hayatsu; T Hayatsu
Journal:  Jpn J Cancer Res       Date:  1989-11
  3 in total

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