| Literature DB >> 3888978 |
Abstract
L-Threonine dehydrogenase, which forms aminoacetone from L-threonine and NAD, has been extensively purified from goat liver. A feedback inhibition of this enzyme has been observed with methylglyoxal. Kinetic data and other experiments indicate that methylglyoxal acts at a site other than the active site of the enzyme. The enzyme contains a single subunit of Mr 89,000. The apparent Km values of the enzyme for L-threonine and NAD were found to be 5.5 and 1 mM, respectively.Entities:
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Year: 1985 PMID： 3888978
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157