Literature DB >> 3888509

Opsonic activity of MCP-1 and MCP-2, cationic peptides from rabbit alveolar macrophages.

J Fleischmann, M E Selsted, R I Lehrer.   

Abstract

MCP-1 and MCP-2, cationic peptides derived from rabbit alveolar macrophages, enhanced the ability of these cells to ingest Staphylococcus aureus, Klebsiella pneumoniae, Bordetella bronchiseptica, and Candida albicans in vitro. The opsonic effect of MCP-1 was potentiated by Ca++ and Mg++ and was associated with binding of the peptide to alveolar macrophages and microorganisms. MCP-1 and MCP-2 may contribute to the ability of alveolar macrophage to ingest microorganisms that gain entry to the lower respiratory tract.

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Year:  1985        PMID： 3888509     DOI： 10.1016/0732-8893(85)90035-5

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  16 in total

1.  Contribution of rabbit leukocyte defensins to the host response in experimental syphilis.

Authors:  L A Borenstein; T Ganz; S Sell; R I Lehrer; J N Miller
Journal:  Infect Immun       Date:  1991-04       Impact factor: 3.441

Review 2.  Direct and alternative antimicrobial mechanisms of neutrophil-derived granule proteins.

Authors:  Oliver Soehnlein
Journal:  J Mol Med (Berl)       Date:  2009-07-31       Impact factor: 4.599

3.  Humanized theta-defensins (retrocyclins) enhance macrophage performance and protect mice from experimental anthrax infections.

Authors:  S Welkos; C K Cote; U Hahn; O Shastak; J Jedermann; J Bozue; G Jung; P Ruchala; P Pratikhya; T Tang; R I Lehrer; W Beyer
Journal:  Antimicrob Agents Chemother       Date:  2011-07-18       Impact factor: 5.191

4.  Evaluation of susceptibility of gram-positive and -negative bacteria to human defensins by using radial diffusion assay.

Authors:  H Takemura; M Kaku; S Kohno; Y Hirakata; H Tanaka; R Yoshida; K Tomono; H Koga; A Wada; T Hirayama; S Kamihira
Journal:  Antimicrob Agents Chemother       Date:  1996-10       Impact factor: 5.191

5.  LL-37 opsonizes and inhibits biofilm formation of Aggregatibacter actinomycetemcomitans at subbactericidal concentrations.

Authors:  Asaf Sol; Ofir Ginesin; Stella Chaushu; Laila Karra; Shunit Coppenhagen-Glazer; Isaac Ginsburg; Gilad Bachrach
Journal:  Infect Immun       Date:  2013-07-08       Impact factor: 3.441

6.  Polymorphic expression of defensins in neutrophils from outbred rats.

Authors:  P Eisenhauer; S S Harwig; D Szklarek; T Ganz; R I Lehrer
Journal:  Infect Immun       Date:  1990-12       Impact factor: 3.441

7.  Neutrophil secretion products regulate anti-bacterial activity in monocytes and macrophages.

Authors:  O Soehnlein; E Kenne; P Rotzius; E E Eriksson; L Lindbom
Journal:  Clin Exp Immunol       Date:  2007-12-07       Impact factor: 4.330

8.  Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages.

Authors:  Oliver Soehnlein; Ylva Kai-Larsen; Robert Frithiof; Ole E Sorensen; Ellinor Kenne; Karin Scharffetter-Kochanek; Einar E Eriksson; Heiko Herwald; Birgitta Agerberth; Lennart Lindbom
Journal:  J Clin Invest       Date:  2008-10       Impact factor: 14.808

9.  The use of antimicrobial peptides in ophthalmology: an experimental study in corneal preservation and the management of bacterial keratitis.

Authors:  Mark J Mannis
Journal:  Trans Am Ophthalmol Soc       Date:  2002

10.  Identification and characterization of a novel antibacterial peptide, avian beta-defensin 2 from ducks.

Authors:  Deying Ma; Ruiqin Wang; Wenyan Liao; Zongxi Han; Shengwang Liu
Journal:  J Microbiol       Date:  2009-10-24       Impact factor: 3.422
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