| Literature DB >> 3888102 |
B E Gilbert, S Z Wilson, V Knight, R B Couch, J M Quarles, L Dure, N Hayes, G Willis.
Abstract
In a double-blind study of influenza in a population of college students in 1984, ribavirin small-particle aerosol treatment of 38 patients (18 treated, 20 control) infected with a new antigenic variant, influenza virus strain A/Victoria/7/83 (H1N1), was associated with statistically significant reductions in the height and duration of fever, systemic symptoms, and virus shedding. Patients received a total of 2.4 g of ribavirin over 42 h during 68 h of hospitalization without any side effects. In addition, in a study of patients infected with influenza virus strain B/Texas/1/84 (seven treated, eight control) treated with ribavirin aerosol showed a trend of more rapid recovery than control patients.Entities:
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Year: 1985 PMID: 3888102 PMCID: PMC176267 DOI: 10.1128/AAC.27.3.309
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191