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Literature DB >> 3886670

Active maturation-promoting factor is present in mature mouse oocytes.

Abstract

Cytoplasmic extracts of meiotically mature mouse oocytes were injected into immature Xenopus laevis oocytes, which underwent germinal vesicle breakdown within 2 h. Germinal vesicle breakdown was not inhibited by incubation of the Xenopus oocytes in cycloheximide (20 micrograms/ml). Identically prepared extracts of meiotically immature mouse oocytes, arrested at the germinal vesicle stage by dibutyryl cyclic AMP (100 micrograms/ml), did not induce germinal vesicle breakdown in Xenopus oocytes. The results show that maturation-promoting factor activity appears during the course of oocyte maturation in the mouse.

Entities: Chemical Species

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Year: 1985 PMID： 3886670 PMCID： PMC2113872 DOI： 10.1083/jcb.100.5.1637

Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539

24 in total

5. Studies on the appearance and nature of a maturation-inducing factor in the cytoplasm of amphibian oocytes exposed to progesterone.

Authors: J K Reynhout; L D Smith
Journal: Dev Biol Date: 1974-06 Impact factor: 3.582

6. Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro.

Authors: W K Cho; S Stern; J D Biggers
Journal: J Exp Zool Date: 1974-03

7. Progesterone induced maturation in oocytes of Xenopus laevis. Appearance of a 'maturation promoting factor' in enucleated oocytes.

Authors: S Schorderet-Slatkine; K C Drury
Journal: Cell Differ Date: 1973-10

8. Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes.

Authors: Y Masui; C L Markert
Journal: J Exp Zool Date: 1971-06

9. In vitro induction of physiological maturation in Rana pipiens oocytes removed from their ovarian follicles.

Authors: L D Smith; R E Ecker; S Subtelny
Journal: Dev Biol Date: 1968-06 Impact factor: 3.582

10. Relative roles of the pituitary, follicle cells, and progesterone in the induction of oocyte maturation in Rana pipiens.

Authors: Y Masui
Journal: J Exp Zool Date: 1967-12

6 in total

Active maturation-promoting factor is present in mature mouse oocytes.

1. Induction of maturation (meiosis) in small Xenopus laevis oocytes by injection of maturation promoting factor.

2. Effects of cyclohexamide on a cytoplasmic factor initiating meiotic naturation in Xenopus oocytes.

3. Relationship between growth and meiotic maturation of the mouse oocyte.

4. Cytoplasmic factor responsible for germinal vesicle breakdown and meiotic maturation in starfish oocyte.

5. Studies on the appearance and nature of a maturation-inducing factor in the cytoplasm of amphibian oocytes exposed to progesterone.

6. Inhibitory effect of dibutyryl cAMP on mouse oocyte maturation in vitro.

7. Progesterone induced maturation in oocytes of Xenopus laevis. Appearance of a 'maturation promoting factor' in enucleated oocytes.

8. Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes.

9. In vitro induction of physiological maturation in Rana pipiens oocytes removed from their ovarian follicles.

10. Relative roles of the pituitary, follicle cells, and progesterone in the induction of oocyte maturation in Rana pipiens.

1. Demonstration of maturation-promoting and -inhibiting activities in mouse oocytes.

2. cdc2 and the regulation of mitosis: six interacting mcs genes.

3. Study of the in vitro maturation of mouse oocytes induced by microinjection of maturation promoting factor (MPF).

4. Metaphase protein phosphorylation in Xenopus laevis eggs.

5. Transformation of sperm nuclei to metaphase chromosomes in the cytoplasm of maturing oocytes of the mouse.

Review 6. Entry into mitosis: a solution to the decades-long enigma of MPF.