Literature DB >> 3883905

The mutagenicity of dinitrochlorobenzene.

H S Black, F F Castrow, J Gerguis.   

Abstract

A sample of dinitrochlorobenzene, determined by gas-liquid chromatography and mass spectrometry to be greater than 98% pure, was tested in the Salmonella typhimurium plate assay. The chemical evoked a marked mutagenic response at all concentrations tested (3 to 150 micrograms per plate). These results confute the suitability of this agent for the treatment of benign skin disorders.

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Year:  1985        PMID: 3883905

Source DB:  PubMed          Journal:  Arch Dermatol        ISSN: 0003-987X


  2 in total

Review 1.  Application of Topical Immunotherapy in the Treatment of Alopecia Areata: A Review and Update.

Authors:  Thipprapai Mahasaksiri; Chaninan Kositkuljorn; Tanaporn Anuntrangsee; Poonkiat Suchonwanit
Journal:  Drug Des Devel Ther       Date:  2021-03-23       Impact factor: 4.162

2.  Human papillomavirus e7 oncoprotein transgenic skin develops an enhanced inflammatory response to 2,4-dinitrochlorobenzene by an arginase-1-dependent mechanism.

Authors:  D Mittal; I H Frazer; L S Tran; A-S Bergot; S R Mattarollo
Journal:  J Invest Dermatol       Date:  2014-04-14       Impact factor: 8.551

  2 in total

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